Bilateral Renal Cortical Necrosis in Meningococcal Meningitis
Bacterial meningitis is a relatively common infection of the cerebrospinal fluid (CSF) and leptomeninges. The clinical picture evolves rapidly and, if treatment is delayed, can result in a variety of long-...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2011/274341 |
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| Summary: | Bacterial meningitis
is a relatively common infection of the
cerebrospinal fluid (CSF) and leptomeninges. The
clinical picture evolves rapidly and, if
treatment is delayed, can result in a variety of
long-term sequelae, including death. Acute
kidney injury in the setting of bacterial
meningitis usually results from hypotension and
volume depletion and resolves with appropriate
treatment. Meningococcaemia with profound
hypotension, and/or disseminated intravascular
coagulopathy (DIC) may very rarely lead to
bilateral renal cortical necrosis. In this
context, renal recovery is extremely unlikely.
We present two cases of meningococcaemia
complicated by bilateral renal cortical necrosis
and, ultimately, end stage kidney disease. We
also present a review of the literature on the
subject. The cases outline the importance of
early aggressive intervention by a
multidisciplinary team. |
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| ISSN: | 2090-6641 2090-665X |