A Virtual Microscopy System to Scan, Evaluate and Archive Biomarker Enhanced Cervical Cytology Slides
Background: Although cytological screening for cervical precancers has led to a reduction of cervical cancer incidence worldwide it is a subjective and variable method with low single-test sensitivity. New biomarkers like p16 that specifically highlight abnormal cervical cells can improve cytology p...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2010-01-01
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| Series: | Cellular Oncology |
| Online Access: | http://dx.doi.org/10.3233/CLO-2009-0508 |
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| _version_ | 1832558943280300032 |
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| author | Niels Grabe Bernd Lahrmann Thora Pommerencke Magnus von Knebel Doeberitz Miriam Reuschenbach Nicolas Wentzensen |
| author_facet | Niels Grabe Bernd Lahrmann Thora Pommerencke Magnus von Knebel Doeberitz Miriam Reuschenbach Nicolas Wentzensen |
| author_sort | Niels Grabe |
| collection | DOAJ |
| description | Background: Although cytological screening for cervical precancers has led to a reduction of cervical cancer incidence worldwide it is a subjective and variable method with low single-test sensitivity. New biomarkers like p16 that specifically highlight abnormal cervical cells can improve cytology performance. Virtual microscopy offers an ideal platform for assisted evaluation and archiving of biomarker-stained slides. |
| format | Article |
| id | doaj-art-846f0772783347a4943e90c54af429f6 |
| institution | Kabale University |
| issn | 1570-5870 1875-8606 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cellular Oncology |
| spelling | doaj-art-846f0772783347a4943e90c54af429f62025-02-03T01:31:11ZengWileyCellular Oncology1570-58701875-86062010-01-01321-210911910.3233/CLO-2009-0508A Virtual Microscopy System to Scan, Evaluate and Archive Biomarker Enhanced Cervical Cytology SlidesNiels Grabe0Bernd Lahrmann1Thora Pommerencke2Magnus von Knebel Doeberitz3Miriam Reuschenbach4Nicolas Wentzensen5Institute of Medical Biometry and Informatics, Section Medical Informatics, University Hospital Heidelberg, Heidelberg, GermanyInstitute of Medical Biometry and Informatics, Section Medical Informatics, University Hospital Heidelberg, Heidelberg, GermanyInstitute of Medical Biometry and Informatics, Section Medical Informatics, University Hospital Heidelberg, Heidelberg, GermanyInstitute of Pathology, Department of Applied Tumor Biology, University Hospital Heidelberg, Heidelberg, GermanyInstitute of Pathology, Department of Applied Tumor Biology, University Hospital Heidelberg, Heidelberg, GermanyInstitute of Pathology, Department of Applied Tumor Biology, University Hospital Heidelberg, Heidelberg, GermanyBackground: Although cytological screening for cervical precancers has led to a reduction of cervical cancer incidence worldwide it is a subjective and variable method with low single-test sensitivity. New biomarkers like p16 that specifically highlight abnormal cervical cells can improve cytology performance. Virtual microscopy offers an ideal platform for assisted evaluation and archiving of biomarker-stained slides.http://dx.doi.org/10.3233/CLO-2009-0508 |
| spellingShingle | Niels Grabe Bernd Lahrmann Thora Pommerencke Magnus von Knebel Doeberitz Miriam Reuschenbach Nicolas Wentzensen A Virtual Microscopy System to Scan, Evaluate and Archive Biomarker Enhanced Cervical Cytology Slides Cellular Oncology |
| title | A Virtual Microscopy System to Scan, Evaluate and Archive Biomarker Enhanced Cervical Cytology Slides |
| title_full | A Virtual Microscopy System to Scan, Evaluate and Archive Biomarker Enhanced Cervical Cytology Slides |
| title_fullStr | A Virtual Microscopy System to Scan, Evaluate and Archive Biomarker Enhanced Cervical Cytology Slides |
| title_full_unstemmed | A Virtual Microscopy System to Scan, Evaluate and Archive Biomarker Enhanced Cervical Cytology Slides |
| title_short | A Virtual Microscopy System to Scan, Evaluate and Archive Biomarker Enhanced Cervical Cytology Slides |
| title_sort | virtual microscopy system to scan evaluate and archive biomarker enhanced cervical cytology slides |
| url | http://dx.doi.org/10.3233/CLO-2009-0508 |
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