Histone H3 K4 trimethylation occurs mainly at the origins of polycistronic transcription in the genome of Leishmania infantum promastigotes and intracellular amastigotes

Histone H3 K4 trimethylation occurs mainly at the origins of polycistronic transcription in the genome of Leishmania infantum promastigotes and intracellular amastigotes

Abstract Background Trypanosomatids include the genera Trypanosoma and Leishmania, which are the etiological agents of important human diseases. These pathogens present unique mechanisms of gene expression characterized by functionally unrelated genes positioned in tandem and organized into polycist...

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Bibliographic Details
Main Authors: Aurora Diotallevi, Stefano Amatori, Giuseppe Persico, Gloria Buffi, Enrica Sordini, Marco Giorgio, Mirco Fanelli, Luca Galluzzi
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Genomics
Subjects:
Amastigote
Epigenomics
H3K4me3
Leishmania infantum
Promastigote
Online Access:https://doi.org/10.1186/s12864-025-11350-1
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https://doi.org/10.1186/s12864-025-11350-1

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