Effects of replacing fishmeal with soybean meal on growth performance, liver antioxidant capacity and intestinal health in juvenile Asian red-tailed catfish (Hemibagrus wyckioides)
The present study was to evaluate the effects of different levels of soybean meal (SBM) substitute for fish meal (FM) on the growth performance, antioxidant capacities, and intestine health of Asian red-tailed catfish, Hemibagrus wyckioides. Five isonitrogenous and isolipidic diets were prepared: th...
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| Language: | English |
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Elsevier
2025-03-01
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| Series: | Aquaculture Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352513425000328 |
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| author | Weijia Cai Xinping Li Minglang Cai Zhe Tang Bo Zhu Mengxi Yang Yi Hu Jihong Dai |
| author_facet | Weijia Cai Xinping Li Minglang Cai Zhe Tang Bo Zhu Mengxi Yang Yi Hu Jihong Dai |
| author_sort | Weijia Cai |
| collection | DOAJ |
| description | The present study was to evaluate the effects of different levels of soybean meal (SBM) substitute for fish meal (FM) on the growth performance, antioxidant capacities, and intestine health of Asian red-tailed catfish, Hemibagrus wyckioides. Five isonitrogenous and isolipidic diets were prepared: the FM diets contained 50 % fish meal, based on which four SBM diets were formulated as substitutes for 15 %, 30 %, 45 % and 60 % FM in the FM group diets, namely SBM15, SBM30, SBM45, and SBM60. Compared with the FM group, the SBM45 and SBM60 groups exhibited significantly elevated serum glutamate pyruvate transaminase (GPT) levels and showed evidence of liver oxidative stress injury. Concurrently, there were decreases in triglyceride (TG) and total cholesterol (TC) levels (P < 0.05). Besides, hepatic antioxidant enzyme activities and nrf2 gene expression levels were markedly upregulated in the SBM45 and SBM60 groups (P < 0.05). In the SBM45 and SBM60 groups, the lamina propria of the intestinal villi became wider, and the number of goblet cells increased. The tight junction proteins zo-1, claudin-4 and occludin were significantly downregulated in the SBM45 and SBM60 groups. At the same time, the pro-inflammatory factors inos, tgf-β, tnf-α and il-1β were significantly upregulated in these two groups (P < 0.05). The SBM45 and SBM60 diets contributed to significant alterations in the intestinal microbiota. In the SBM60 group, the relative abundances of Cetobacterium and Lawsonia significantly increased, and the intestinal microbiota function was predicted to undergo upregulation of complex carbohydrate metabolism and fermentation. The results of the broken-line regression analysis for FCR and SGR indicate that the optimal substitution level of FM with SBM for H. wyckioides feed is estimated to be 36.83 %-37.31 %. Substitution levels exceeding this range, such as 45 % and 60 %, adversely affect liver and intestinal health. |
| format | Article |
| id | doaj-art-842ed5cbcb374e989ecb15f75553d97e |
| institution | Kabale University |
| issn | 2352-5134 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Aquaculture Reports |
| spelling | doaj-art-842ed5cbcb374e989ecb15f75553d97e2025-02-06T05:12:25ZengElsevierAquaculture Reports2352-51342025-03-0140102646Effects of replacing fishmeal with soybean meal on growth performance, liver antioxidant capacity and intestinal health in juvenile Asian red-tailed catfish (Hemibagrus wyckioides)Weijia Cai0Xinping Li1Minglang Cai2Zhe Tang3Bo Zhu4Mengxi Yang5Yi Hu6Jihong Dai7Hunan Engineering Research Center for Utilization of Characteristics of Aquatic Resources, Hunan Agricultural University, Changsha 410128, ChinaXishuangbanna Indigenous Fish Research and Breeding Center, Jinghong 666109, ChinaHunan Engineering Research Center for Utilization of Characteristics of Aquatic Resources, Hunan Agricultural University, Changsha 410128, ChinaHunan Engineering Research Center for Utilization of Characteristics of Aquatic Resources, Hunan Agricultural University, Changsha 410128, ChinaHunan Engineering Research Center for Utilization of Characteristics of Aquatic Resources, Hunan Agricultural University, Changsha 410128, ChinaHunan Engineering Research Center for Utilization of Characteristics of Aquatic Resources, Hunan Agricultural University, Changsha 410128, ChinaHunan Engineering Research Center for Utilization of Characteristics of Aquatic Resources, Hunan Agricultural University, Changsha 410128, ChinaHunan Engineering Research Center for Utilization of Characteristics of Aquatic Resources, Hunan Agricultural University, Changsha 410128, China; Corresponding author.The present study was to evaluate the effects of different levels of soybean meal (SBM) substitute for fish meal (FM) on the growth performance, antioxidant capacities, and intestine health of Asian red-tailed catfish, Hemibagrus wyckioides. Five isonitrogenous and isolipidic diets were prepared: the FM diets contained 50 % fish meal, based on which four SBM diets were formulated as substitutes for 15 %, 30 %, 45 % and 60 % FM in the FM group diets, namely SBM15, SBM30, SBM45, and SBM60. Compared with the FM group, the SBM45 and SBM60 groups exhibited significantly elevated serum glutamate pyruvate transaminase (GPT) levels and showed evidence of liver oxidative stress injury. Concurrently, there were decreases in triglyceride (TG) and total cholesterol (TC) levels (P < 0.05). Besides, hepatic antioxidant enzyme activities and nrf2 gene expression levels were markedly upregulated in the SBM45 and SBM60 groups (P < 0.05). In the SBM45 and SBM60 groups, the lamina propria of the intestinal villi became wider, and the number of goblet cells increased. The tight junction proteins zo-1, claudin-4 and occludin were significantly downregulated in the SBM45 and SBM60 groups. At the same time, the pro-inflammatory factors inos, tgf-β, tnf-α and il-1β were significantly upregulated in these two groups (P < 0.05). The SBM45 and SBM60 diets contributed to significant alterations in the intestinal microbiota. In the SBM60 group, the relative abundances of Cetobacterium and Lawsonia significantly increased, and the intestinal microbiota function was predicted to undergo upregulation of complex carbohydrate metabolism and fermentation. The results of the broken-line regression analysis for FCR and SGR indicate that the optimal substitution level of FM with SBM for H. wyckioides feed is estimated to be 36.83 %-37.31 %. Substitution levels exceeding this range, such as 45 % and 60 %, adversely affect liver and intestinal health.http://www.sciencedirect.com/science/article/pii/S2352513425000328Hemibagrus wyckioidesSoybean mealFish meal alternativeGrowth performanceIntestine health |
| spellingShingle | Weijia Cai Xinping Li Minglang Cai Zhe Tang Bo Zhu Mengxi Yang Yi Hu Jihong Dai Effects of replacing fishmeal with soybean meal on growth performance, liver antioxidant capacity and intestinal health in juvenile Asian red-tailed catfish (Hemibagrus wyckioides) Aquaculture Reports Hemibagrus wyckioides Soybean meal Fish meal alternative Growth performance Intestine health |
| title | Effects of replacing fishmeal with soybean meal on growth performance, liver antioxidant capacity and intestinal health in juvenile Asian red-tailed catfish (Hemibagrus wyckioides) |
| title_full | Effects of replacing fishmeal with soybean meal on growth performance, liver antioxidant capacity and intestinal health in juvenile Asian red-tailed catfish (Hemibagrus wyckioides) |
| title_fullStr | Effects of replacing fishmeal with soybean meal on growth performance, liver antioxidant capacity and intestinal health in juvenile Asian red-tailed catfish (Hemibagrus wyckioides) |
| title_full_unstemmed | Effects of replacing fishmeal with soybean meal on growth performance, liver antioxidant capacity and intestinal health in juvenile Asian red-tailed catfish (Hemibagrus wyckioides) |
| title_short | Effects of replacing fishmeal with soybean meal on growth performance, liver antioxidant capacity and intestinal health in juvenile Asian red-tailed catfish (Hemibagrus wyckioides) |
| title_sort | effects of replacing fishmeal with soybean meal on growth performance liver antioxidant capacity and intestinal health in juvenile asian red tailed catfish hemibagrus wyckioides |
| topic | Hemibagrus wyckioides Soybean meal Fish meal alternative Growth performance Intestine health |
| url | http://www.sciencedirect.com/science/article/pii/S2352513425000328 |
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