Synthesis, Characterization, and Evaluation of Antimicrobial Activities of Chitosan and Carboxymethyl Chitosan Schiff-Base/Silver Nanoparticles
Schiff-bases of chitosan (CS) and carboxymethyl chitosan (CMCS)/silver nanoparticles (AgNPs) have been synthesized, characterized, and evaluated as antimicrobial agents against two Gram +ve bacteria (Bacillus cereus and Staphylococcus aureus) and two Gram −ve bacteria (Escherichia coli and Pseudomon...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2017/1434320 |
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| author | Ahmed M. Khalil Reham A. Abdel-Monem Osama M. Darwesh Ahmed I. Hashim Afaf A. Nada Samira T. Rabie |
| author_facet | Ahmed M. Khalil Reham A. Abdel-Monem Osama M. Darwesh Ahmed I. Hashim Afaf A. Nada Samira T. Rabie |
| author_sort | Ahmed M. Khalil |
| collection | DOAJ |
| description | Schiff-bases of chitosan (CS) and carboxymethyl chitosan (CMCS)/silver nanoparticles (AgNPs) have been synthesized, characterized, and evaluated as antimicrobial agents against two Gram +ve bacteria (Bacillus cereus and Staphylococcus aureus) and two Gram −ve bacteria (Escherichia coli and Pseudomonas aeruginosa) in addition to Candida albicans as a fungus. The in situ reactions of CS and/or CMCS with some pyrazole aldehyde derivatives in acidic media containing silver nitrate to yield silver nanoparticles loaded onto CS and CMCS/Schiff-bases were carried out. Characterizations of the prepared compounds via FTIR spectroscopy, SEM, TEM, and TGA were carried out. Schiff-bases/silver nanoparticles of CS and CMCS showed higher antimicrobial activity than the blank CS and CMCS. The presence of AgNO3 (3% wt%) displayed high antibacterial efficiencies with inhibition zones in the extent of 19–39 mm. TEM analysis showed that the size of the silver nanoparticles is in the range of 4–28 nm for the prepared nanocomposites. |
| format | Article |
| id | doaj-art-84282c18de8f49fe90a56727f1ef35a6 |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-84282c18de8f49fe90a56727f1ef35a62025-02-03T06:10:52ZengWileyJournal of Chemistry2090-90632090-90712017-01-01201710.1155/2017/14343201434320Synthesis, Characterization, and Evaluation of Antimicrobial Activities of Chitosan and Carboxymethyl Chitosan Schiff-Base/Silver NanoparticlesAhmed M. Khalil0Reham A. Abdel-Monem1Osama M. Darwesh2Ahmed I. Hashim3Afaf A. Nada4Samira T. Rabie5Photochemistry Department, National Research Centre, El Buhouth St., Dokki, Giza 12622, EgyptPhotochemistry Department, National Research Centre, El Buhouth St., Dokki, Giza 12622, EgyptEnvironmental Biotechnology and Nanotechnology, Agricultural Microbiology Department, National Research Centre, El Buhouth St., Dokki, Giza 12622, EgyptChemistry Department, Faculty of Science, Ain Shams University, Cairo, EgyptPhotochemistry Department, National Research Centre, El Buhouth St., Dokki, Giza 12622, EgyptPhotochemistry Department, National Research Centre, El Buhouth St., Dokki, Giza 12622, EgyptSchiff-bases of chitosan (CS) and carboxymethyl chitosan (CMCS)/silver nanoparticles (AgNPs) have been synthesized, characterized, and evaluated as antimicrobial agents against two Gram +ve bacteria (Bacillus cereus and Staphylococcus aureus) and two Gram −ve bacteria (Escherichia coli and Pseudomonas aeruginosa) in addition to Candida albicans as a fungus. The in situ reactions of CS and/or CMCS with some pyrazole aldehyde derivatives in acidic media containing silver nitrate to yield silver nanoparticles loaded onto CS and CMCS/Schiff-bases were carried out. Characterizations of the prepared compounds via FTIR spectroscopy, SEM, TEM, and TGA were carried out. Schiff-bases/silver nanoparticles of CS and CMCS showed higher antimicrobial activity than the blank CS and CMCS. The presence of AgNO3 (3% wt%) displayed high antibacterial efficiencies with inhibition zones in the extent of 19–39 mm. TEM analysis showed that the size of the silver nanoparticles is in the range of 4–28 nm for the prepared nanocomposites.http://dx.doi.org/10.1155/2017/1434320 |
| spellingShingle | Ahmed M. Khalil Reham A. Abdel-Monem Osama M. Darwesh Ahmed I. Hashim Afaf A. Nada Samira T. Rabie Synthesis, Characterization, and Evaluation of Antimicrobial Activities of Chitosan and Carboxymethyl Chitosan Schiff-Base/Silver Nanoparticles Journal of Chemistry |
| title | Synthesis, Characterization, and Evaluation of Antimicrobial Activities of Chitosan and Carboxymethyl Chitosan Schiff-Base/Silver Nanoparticles |
| title_full | Synthesis, Characterization, and Evaluation of Antimicrobial Activities of Chitosan and Carboxymethyl Chitosan Schiff-Base/Silver Nanoparticles |
| title_fullStr | Synthesis, Characterization, and Evaluation of Antimicrobial Activities of Chitosan and Carboxymethyl Chitosan Schiff-Base/Silver Nanoparticles |
| title_full_unstemmed | Synthesis, Characterization, and Evaluation of Antimicrobial Activities of Chitosan and Carboxymethyl Chitosan Schiff-Base/Silver Nanoparticles |
| title_short | Synthesis, Characterization, and Evaluation of Antimicrobial Activities of Chitosan and Carboxymethyl Chitosan Schiff-Base/Silver Nanoparticles |
| title_sort | synthesis characterization and evaluation of antimicrobial activities of chitosan and carboxymethyl chitosan schiff base silver nanoparticles |
| url | http://dx.doi.org/10.1155/2017/1434320 |
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