Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents

The review is mainly concerned with the protonation equilibria of biologically active ligands like amino acids, peptides, DNA constituents, and amino acid esters in nonaqueous media. Equilibrium concentrations of proton-ligand formation as a function of pH were investigated. Also, thermodynamics ass...

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Main Authors: Ahmed A. El-Sherif, Mohamed M. Shoukry, Abeer T. Abd Elkarim, Mohammad H. Barakat
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Bioinorganic Chemistry and Applications
Online Access:http://dx.doi.org/10.1155/2014/626719
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author Ahmed A. El-Sherif
Mohamed M. Shoukry
Abeer T. Abd Elkarim
Mohammad H. Barakat
author_facet Ahmed A. El-Sherif
Mohamed M. Shoukry
Abeer T. Abd Elkarim
Mohammad H. Barakat
author_sort Ahmed A. El-Sherif
collection DOAJ
description The review is mainly concerned with the protonation equilibria of biologically active ligands like amino acids, peptides, DNA constituents, and amino acid esters in nonaqueous media. Equilibrium concentrations of proton-ligand formation as a function of pH were investigated. Also, thermodynamics associated with protonation equilibria were also discussed.
format Article
id doaj-art-8416ebcf3ea041f1b09980eb52b44515
institution Kabale University
issn 1565-3633
1687-479X
language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Bioinorganic Chemistry and Applications
spelling doaj-art-8416ebcf3ea041f1b09980eb52b445152025-02-03T07:23:34ZengWileyBioinorganic Chemistry and Applications1565-36331687-479X2014-01-01201410.1155/2014/626719626719Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic SolventsAhmed A. El-Sherif0Mohamed M. Shoukry1Abeer T. Abd Elkarim2Mohammad H. Barakat3Chemistry Department, Faculty of Science, Cairo University, Giza, EgyptChemistry Department, Faculty of Science, Cairo University, Giza, EgyptChemistry Department, Faculty of Science, Cairo University, Giza, EgyptHolding Company for Water and Waste Water, The Reference Laboratory for Drinking Water, Inorganic Laboratory, Cairo, EgyptThe review is mainly concerned with the protonation equilibria of biologically active ligands like amino acids, peptides, DNA constituents, and amino acid esters in nonaqueous media. Equilibrium concentrations of proton-ligand formation as a function of pH were investigated. Also, thermodynamics associated with protonation equilibria were also discussed.http://dx.doi.org/10.1155/2014/626719
spellingShingle Ahmed A. El-Sherif
Mohamed M. Shoukry
Abeer T. Abd Elkarim
Mohammad H. Barakat
Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents
Bioinorganic Chemistry and Applications
title Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents
title_full Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents
title_fullStr Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents
title_full_unstemmed Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents
title_short Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents
title_sort protonation equilibria of biologically active ligands in mixed aqueous organic solvents
url http://dx.doi.org/10.1155/2014/626719
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AT mohamedmshoukry protonationequilibriaofbiologicallyactiveligandsinmixedaqueousorganicsolvents
AT abeertabdelkarim protonationequilibriaofbiologicallyactiveligandsinmixedaqueousorganicsolvents
AT mohammadhbarakat protonationequilibriaofbiologicallyactiveligandsinmixedaqueousorganicsolvents