Jejunal Diverticulosis Probably Leading to Pylephlebitis of the Superior Mesenteric Vein

Thrombophlebitis of the portal vein (pylephlebitis) is a rare but serious condition with a high mortality rate of 11-50%. A 56-year-old male patient presented with a two-day history of postprandial, colic-like epigastric pain, nausea, fever, chills, and diarrhea. Clinical workup showed peritonism, l...

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Main Authors: Julia Bockmeyer, Stephanie Taha-Mehlitz, Nickolaus Heeren, Stefan Ristic, Jürg Metzger, Jörn-Markus Gass
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2020/2343218
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author Julia Bockmeyer
Stephanie Taha-Mehlitz
Nickolaus Heeren
Stefan Ristic
Jürg Metzger
Jörn-Markus Gass
author_facet Julia Bockmeyer
Stephanie Taha-Mehlitz
Nickolaus Heeren
Stefan Ristic
Jürg Metzger
Jörn-Markus Gass
author_sort Julia Bockmeyer
collection DOAJ
description Thrombophlebitis of the portal vein (pylephlebitis) is a rare but serious condition with a high mortality rate of 11-50%. A 56-year-old male patient presented with a two-day history of postprandial, colic-like epigastric pain, nausea, fever, chills, and diarrhea. Clinical workup showed peritonism, leukocytosis, and elevated C-reactive protein (CRP). A computed tomography (CT) scan revealed a long-segment, partial thrombosis of the superior mesenteric vein as well as gas in the portal venous system. Additionally, extensive jejunal diverticulosis was present. Pylephlebitis mostly results from intestinal infections, e.g., appendicitis or diverticulitis. We assumed that the patient had suffered from a self-limiting episode of jejunal diverticulitis leading to septic thrombosis. Initially, antibiotic therapy and anticoagulation with heparin were administered. The patient deteriorated, and due to increasing abdominal defense, fever, and hypotension, a diagnostic laparoscopy was performed. Bowel ischemia could be ruled out, and after changing antibiotic therapy, the patient’s condition improved. He was discharged without any further complications and without complaints on day 13. An underlying coagulopathy like myeloproliferative neoplasm or antiphospholipid syndrome could be ruled out.
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spelling doaj-art-84024023b06e47388ae9c320b20122542025-02-03T06:46:40ZengWileyCase Reports in Surgery2090-69002090-69192020-01-01202010.1155/2020/23432182343218Jejunal Diverticulosis Probably Leading to Pylephlebitis of the Superior Mesenteric VeinJulia Bockmeyer0Stephanie Taha-Mehlitz1Nickolaus Heeren2Stefan Ristic3Jürg Metzger4Jörn-Markus Gass5Department of General Surgery, Cantonal Hospital of Lucerne, Spitalstrasse, 6000 Lucerne 16, SwitzerlandClarunis, Department of Visceral Surgery, University Centre for Gastrointestinal and Liver Diseases, St. Clara Hospital and University Hospital, Basel Kleinriehenstrasse 30 4058, SwitzerlandDepartment of General Surgery, Cantonal Hospital of Lucerne, Spitalstrasse, 6000 Lucerne 16, SwitzerlandDepartment of General Surgery, Cantonal Hospital of Nidwalden, Ennetmooserstrasse, 6370 Stans, SwitzerlandDepartment of General Surgery, Cantonal Hospital of Lucerne, Spitalstrasse, 6000 Lucerne 16, SwitzerlandDepartment of General Surgery, Cantonal Hospital of Lucerne, Spitalstrasse, 6000 Lucerne 16, SwitzerlandThrombophlebitis of the portal vein (pylephlebitis) is a rare but serious condition with a high mortality rate of 11-50%. A 56-year-old male patient presented with a two-day history of postprandial, colic-like epigastric pain, nausea, fever, chills, and diarrhea. Clinical workup showed peritonism, leukocytosis, and elevated C-reactive protein (CRP). A computed tomography (CT) scan revealed a long-segment, partial thrombosis of the superior mesenteric vein as well as gas in the portal venous system. Additionally, extensive jejunal diverticulosis was present. Pylephlebitis mostly results from intestinal infections, e.g., appendicitis or diverticulitis. We assumed that the patient had suffered from a self-limiting episode of jejunal diverticulitis leading to septic thrombosis. Initially, antibiotic therapy and anticoagulation with heparin were administered. The patient deteriorated, and due to increasing abdominal defense, fever, and hypotension, a diagnostic laparoscopy was performed. Bowel ischemia could be ruled out, and after changing antibiotic therapy, the patient’s condition improved. He was discharged without any further complications and without complaints on day 13. An underlying coagulopathy like myeloproliferative neoplasm or antiphospholipid syndrome could be ruled out.http://dx.doi.org/10.1155/2020/2343218
spellingShingle Julia Bockmeyer
Stephanie Taha-Mehlitz
Nickolaus Heeren
Stefan Ristic
Jürg Metzger
Jörn-Markus Gass
Jejunal Diverticulosis Probably Leading to Pylephlebitis of the Superior Mesenteric Vein
Case Reports in Surgery
title Jejunal Diverticulosis Probably Leading to Pylephlebitis of the Superior Mesenteric Vein
title_full Jejunal Diverticulosis Probably Leading to Pylephlebitis of the Superior Mesenteric Vein
title_fullStr Jejunal Diverticulosis Probably Leading to Pylephlebitis of the Superior Mesenteric Vein
title_full_unstemmed Jejunal Diverticulosis Probably Leading to Pylephlebitis of the Superior Mesenteric Vein
title_short Jejunal Diverticulosis Probably Leading to Pylephlebitis of the Superior Mesenteric Vein
title_sort jejunal diverticulosis probably leading to pylephlebitis of the superior mesenteric vein
url http://dx.doi.org/10.1155/2020/2343218
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