Examining the relationships between self-stigma, loneliness, depressive symptoms, and suicidal ideation among people with bipolar disorder

Abstract People diagnosed with bipolar disorder (BD) commonly experience self-stigma, which negatively affects various health outcomes. The aim of the present study was to elucidate the mechanisms through which self-stigma may contribute to suicidality among bipolar patients by investigating the med...

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Main Authors: Piotr Świtaj, Paweł Grygiel, Joanna Leciak, Izabela Stefaniak, Sylwia Opozda-Suder, Marta Anczewska
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-87559-7
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author Piotr Świtaj
Paweł Grygiel
Joanna Leciak
Izabela Stefaniak
Sylwia Opozda-Suder
Marta Anczewska
author_facet Piotr Świtaj
Paweł Grygiel
Joanna Leciak
Izabela Stefaniak
Sylwia Opozda-Suder
Marta Anczewska
author_sort Piotr Świtaj
collection DOAJ
description Abstract People diagnosed with bipolar disorder (BD) commonly experience self-stigma, which negatively affects various health outcomes. The aim of the present study was to elucidate the mechanisms through which self-stigma may contribute to suicidality among bipolar patients by investigating the mediating roles of loneliness and depressive symptoms. A total of 140 patients with BD were cross-sectionally assessed with self-report scales measuring self-stigma, loneliness, depressive symptoms and suicidal ideation, and with a clinician-rated scale evaluating overall psychopathology. Path analysis was used to analyze the data. Self-stigma was directly related to more severe loneliness, depressive symptoms and suicidal thoughts. There were also significant direct effects of loneliness on depressive symptoms and depressive symptoms on suicidal ideation. The direct effect of loneliness on suicidality was non-significant. The following indirect effects on suicidal ideation were found: from self-stigma via depressive symptoms, from loneliness via depressive symptoms and a sequential effect from self-stigma through loneliness and depressive symptoms. Our findings clearly indicate that interventions aiming to reduce the risk of suicide among people with BD should be comprehensive and take into account not only psychiatric symptoms, but also social context and the psychological aspects of living with this diagnosis.
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spelling doaj-art-83cebee293194e77aa8bdbf67144a37a2025-02-02T12:21:22ZengNature PortfolioScientific Reports2045-23222025-01-0115111010.1038/s41598-025-87559-7Examining the relationships between self-stigma, loneliness, depressive symptoms, and suicidal ideation among people with bipolar disorderPiotr Świtaj0Paweł Grygiel1Joanna Leciak2Izabela Stefaniak3Sylwia Opozda-Suder4Marta Anczewska5Maria Sklodowska-Curie Medical Academy in WarsawInstitute of Education, Jagiellonian University in CracowFirst Department of Psychiatry, Institute of Psychiatry and Neurology in WarsawFirst Department of Psychiatry, Institute of Psychiatry and Neurology in WarsawInstitute of Education, Jagiellonian University in CracowFirst Department of Psychiatry, Institute of Psychiatry and Neurology in WarsawAbstract People diagnosed with bipolar disorder (BD) commonly experience self-stigma, which negatively affects various health outcomes. The aim of the present study was to elucidate the mechanisms through which self-stigma may contribute to suicidality among bipolar patients by investigating the mediating roles of loneliness and depressive symptoms. A total of 140 patients with BD were cross-sectionally assessed with self-report scales measuring self-stigma, loneliness, depressive symptoms and suicidal ideation, and with a clinician-rated scale evaluating overall psychopathology. Path analysis was used to analyze the data. Self-stigma was directly related to more severe loneliness, depressive symptoms and suicidal thoughts. There were also significant direct effects of loneliness on depressive symptoms and depressive symptoms on suicidal ideation. The direct effect of loneliness on suicidality was non-significant. The following indirect effects on suicidal ideation were found: from self-stigma via depressive symptoms, from loneliness via depressive symptoms and a sequential effect from self-stigma through loneliness and depressive symptoms. Our findings clearly indicate that interventions aiming to reduce the risk of suicide among people with BD should be comprehensive and take into account not only psychiatric symptoms, but also social context and the psychological aspects of living with this diagnosis.https://doi.org/10.1038/s41598-025-87559-7Internalized stigmaSuicidalityLonelinessDepressionBipolar disorder
spellingShingle Piotr Świtaj
Paweł Grygiel
Joanna Leciak
Izabela Stefaniak
Sylwia Opozda-Suder
Marta Anczewska
Examining the relationships between self-stigma, loneliness, depressive symptoms, and suicidal ideation among people with bipolar disorder
Scientific Reports
Internalized stigma
Suicidality
Loneliness
Depression
Bipolar disorder
title Examining the relationships between self-stigma, loneliness, depressive symptoms, and suicidal ideation among people with bipolar disorder
title_full Examining the relationships between self-stigma, loneliness, depressive symptoms, and suicidal ideation among people with bipolar disorder
title_fullStr Examining the relationships between self-stigma, loneliness, depressive symptoms, and suicidal ideation among people with bipolar disorder
title_full_unstemmed Examining the relationships between self-stigma, loneliness, depressive symptoms, and suicidal ideation among people with bipolar disorder
title_short Examining the relationships between self-stigma, loneliness, depressive symptoms, and suicidal ideation among people with bipolar disorder
title_sort examining the relationships between self stigma loneliness depressive symptoms and suicidal ideation among people with bipolar disorder
topic Internalized stigma
Suicidality
Loneliness
Depression
Bipolar disorder
url https://doi.org/10.1038/s41598-025-87559-7
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