Respiratory Failure Associated with the Lipodystrophy Syndrome in an HIV-Positive Patient with Compromised Lung Function

Protease inhibitors, used as treatment in human immunodeficiency virus (HIV) infection, are associated with a syndrome of peripheral lipodystrophy, central adiposity, hyperlipidemia and insulin resistance. An HIV-positive patient with chronic obstructive pulmonary disease is presented who developed...

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Main Authors: Natasha Press, Valentina Montessori, Tony R Bai, Julio Montaner
Format: Article
Language:English
Published: Wiley 2001-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2001/454835
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author Natasha Press
Valentina Montessori
Tony R Bai
Julio Montaner
author_facet Natasha Press
Valentina Montessori
Tony R Bai
Julio Montaner
author_sort Natasha Press
collection DOAJ
description Protease inhibitors, used as treatment in human immunodeficiency virus (HIV) infection, are associated with a syndrome of peripheral lipodystrophy, central adiposity, hyperlipidemia and insulin resistance. An HIV-positive patient with chronic obstructive pulmonary disease is presented who developed the lipodystrophy syndrome that is associated with the use of protease inhibitors. It is postulated that the lipodystrophy syndrome further compromised his lung function, leading to respiratory failure. Patients who have pulmonary disease and are taking protease inhibitors require monitoring of clinical status and pulmonary function tests.
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institution Kabale University
issn 1198-2241
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publishDate 2001-01-01
publisher Wiley
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series Canadian Respiratory Journal
spelling doaj-art-83caeabcf7de4ca7a8b75feaa14811152025-02-03T05:53:15ZengWileyCanadian Respiratory Journal1198-22412001-01-018427928210.1155/2001/454835Respiratory Failure Associated with the Lipodystrophy Syndrome in an HIV-Positive Patient with Compromised Lung FunctionNatasha Press0Valentina Montessori1Tony R Bai2Julio Montaner3Division of Infectious Diseases, St Paul’s Hospital, University of British Columbia, Vancouver, British Columbia, CanadaDivision of Infectious Diseases, St Paul’s Hospital, University of British Columbia, Vancouver, British Columbia, CanadaDivision of Respirology, St Paul’s Hospital, University of British Columbia, Vancouver, British Columbia, CanadaBC Centre for Excellence in HIV and AIDS, St Paul’s Hospital, Vancouver, British Columbia, CanadaProtease inhibitors, used as treatment in human immunodeficiency virus (HIV) infection, are associated with a syndrome of peripheral lipodystrophy, central adiposity, hyperlipidemia and insulin resistance. An HIV-positive patient with chronic obstructive pulmonary disease is presented who developed the lipodystrophy syndrome that is associated with the use of protease inhibitors. It is postulated that the lipodystrophy syndrome further compromised his lung function, leading to respiratory failure. Patients who have pulmonary disease and are taking protease inhibitors require monitoring of clinical status and pulmonary function tests.http://dx.doi.org/10.1155/2001/454835
spellingShingle Natasha Press
Valentina Montessori
Tony R Bai
Julio Montaner
Respiratory Failure Associated with the Lipodystrophy Syndrome in an HIV-Positive Patient with Compromised Lung Function
Canadian Respiratory Journal
title Respiratory Failure Associated with the Lipodystrophy Syndrome in an HIV-Positive Patient with Compromised Lung Function
title_full Respiratory Failure Associated with the Lipodystrophy Syndrome in an HIV-Positive Patient with Compromised Lung Function
title_fullStr Respiratory Failure Associated with the Lipodystrophy Syndrome in an HIV-Positive Patient with Compromised Lung Function
title_full_unstemmed Respiratory Failure Associated with the Lipodystrophy Syndrome in an HIV-Positive Patient with Compromised Lung Function
title_short Respiratory Failure Associated with the Lipodystrophy Syndrome in an HIV-Positive Patient with Compromised Lung Function
title_sort respiratory failure associated with the lipodystrophy syndrome in an hiv positive patient with compromised lung function
url http://dx.doi.org/10.1155/2001/454835
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AT tonyrbai respiratoryfailureassociatedwiththelipodystrophysyndromeinanhivpositivepatientwithcompromisedlungfunction
AT juliomontaner respiratoryfailureassociatedwiththelipodystrophysyndromeinanhivpositivepatientwithcompromisedlungfunction