Functional Parathyroid Cyst: A Rare Cause of Malignant Hypercalcemia with Primary Hyperparathyroidism—A Case Report and Review of the Literature
Parathyroid cysts are rare lesions found in the neck and anterior mediastinum. They are often nonfunctional (>90%) and rarely in the functional form. This paper discusses a case of severe hypercalcemia (23 mg/dL) secondary to a rare functional parathyroid cyst. The patient was later found to have...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/851941 |
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| author | Areej Khan Yusra Khan Shahzad Raza Ghulam Akbar Monis Khan Nauman Diwan Wajih Rizvi |
| author_facet | Areej Khan Yusra Khan Shahzad Raza Ghulam Akbar Monis Khan Nauman Diwan Wajih Rizvi |
| author_sort | Areej Khan |
| collection | DOAJ |
| description | Parathyroid cysts are rare lesions found in the neck and anterior mediastinum. They are often nonfunctional (>90%) and rarely in the functional form. This paper discusses a case of severe hypercalcemia (23 mg/dL) secondary to a rare functional parathyroid cyst. The patient was later found to have a hemorrhagic cyst with compression of the right recurrent laryngeal nerve. Preoperative diagnosis of the lesion was parathyroid carcinoma. However, reexploration of the parathyroid mass along with microscopic study confirmed the diagnosis of a parathyroid cyst. Following cystectomy, the patient restored her baseline functional status with preservation of the right recurrent laryngeal nerve. Postoperative followup three years later showed no evidence of cyst recurrence. This paper illustrates the rare presentation of parathyroid functional cysts with severe hypercalcemia and primary hyperparathyroidism. Physicians should be aware of the presence of hemorrhage, inflammation, and compressive symptoms in these cysts which mimic parathyroid carcinoma. These patients should be managed with aggressive medical and surgical intervention. |
| format | Article |
| id | doaj-art-83c07926910d4f4891c461d02a1ac75f |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-83c07926910d4f4891c461d02a1ac75f2025-02-03T06:13:37ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/851941851941Functional Parathyroid Cyst: A Rare Cause of Malignant Hypercalcemia with Primary Hyperparathyroidism—A Case Report and Review of the LiteratureAreej Khan0Yusra Khan1Shahzad Raza2Ghulam Akbar3Monis Khan4Nauman Diwan5Wajih Rizvi6Department of Internal Medicine, Brookdale University Hospital and Medical Center, Brooklyn, NY 11212, USABronx Lebanon Hospital, New York, NY 10457, USADepartment of Internal Medicine, Brookdale University Hospital and Medical Center, Brooklyn, NY 11212, USAMcMaster University, Hamilton, ON, L8N 3Z5, CanadaRaritan Bay Medical Center, New Jersey, NJ 08857, USADepartment of R-Endocrinology, Division of Endocrinology and Metabolism, Robertwood Johnson University of Medicine and Dentistry (UMDNJ), Hamilton, NJ 08690, USADepartment of R-Endocrinology, Division of Endocrinology and Metabolism, Robertwood Johnson University of Medicine and Dentistry (UMDNJ), Hamilton, NJ 08690, USAParathyroid cysts are rare lesions found in the neck and anterior mediastinum. They are often nonfunctional (>90%) and rarely in the functional form. This paper discusses a case of severe hypercalcemia (23 mg/dL) secondary to a rare functional parathyroid cyst. The patient was later found to have a hemorrhagic cyst with compression of the right recurrent laryngeal nerve. Preoperative diagnosis of the lesion was parathyroid carcinoma. However, reexploration of the parathyroid mass along with microscopic study confirmed the diagnosis of a parathyroid cyst. Following cystectomy, the patient restored her baseline functional status with preservation of the right recurrent laryngeal nerve. Postoperative followup three years later showed no evidence of cyst recurrence. This paper illustrates the rare presentation of parathyroid functional cysts with severe hypercalcemia and primary hyperparathyroidism. Physicians should be aware of the presence of hemorrhage, inflammation, and compressive symptoms in these cysts which mimic parathyroid carcinoma. These patients should be managed with aggressive medical and surgical intervention.http://dx.doi.org/10.1155/2012/851941 |
| spellingShingle | Areej Khan Yusra Khan Shahzad Raza Ghulam Akbar Monis Khan Nauman Diwan Wajih Rizvi Functional Parathyroid Cyst: A Rare Cause of Malignant Hypercalcemia with Primary Hyperparathyroidism—A Case Report and Review of the Literature Case Reports in Medicine |
| title | Functional Parathyroid Cyst: A Rare Cause of Malignant Hypercalcemia with Primary Hyperparathyroidism—A Case Report and Review of the Literature |
| title_full | Functional Parathyroid Cyst: A Rare Cause of Malignant Hypercalcemia with Primary Hyperparathyroidism—A Case Report and Review of the Literature |
| title_fullStr | Functional Parathyroid Cyst: A Rare Cause of Malignant Hypercalcemia with Primary Hyperparathyroidism—A Case Report and Review of the Literature |
| title_full_unstemmed | Functional Parathyroid Cyst: A Rare Cause of Malignant Hypercalcemia with Primary Hyperparathyroidism—A Case Report and Review of the Literature |
| title_short | Functional Parathyroid Cyst: A Rare Cause of Malignant Hypercalcemia with Primary Hyperparathyroidism—A Case Report and Review of the Literature |
| title_sort | functional parathyroid cyst a rare cause of malignant hypercalcemia with primary hyperparathyroidism a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2012/851941 |
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