The Comorbidity of Depression and Diabetes Is Involved in the Decidual Protein Induced by Progesterone 1 (Depp1) Dysfunction in the Medial Prefrontal Cortex

The Comorbidity of Depression and Diabetes Is Involved in the Decidual Protein Induced by Progesterone 1 (Depp1) Dysfunction in the Medial Prefrontal Cortex

Background: There is a high rate of depressive symptoms such as irritability, anhedonia, fatigue, and hypersomnia in patients with type 2 diabetes mellitus (T2DM). However, the causes and underlying mechanisms of the comorbidity of depression and diabetes remain unknown. Methods: For the first time,...

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Bibliographic Details
Main Authors: Chen Xu, Mengxing Liao, Shize Zhang, Yuang Chen, Xinyue Shulai, Guangji Wang, Jiye Aa
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Metabolites
Subjects:
depression
diabetes
glucose metabolism
DEPP1
mPFC
synaptic protein
Online Access:https://www.mdpi.com/2218-1989/15/1/34
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