Prostate Cancer Severity Associations with Neighborhood Deprivation
Background. The goal of this paper was to examine neighborhood deprivation and prostate cancer severity. Methods. We studied African American and Caucasian prostate cancer cases from the Pennsylvania State Cancer Registry. Census tract-level variables and deprivation scores were examined in relatio...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Prostate Cancer |
| Online Access: | http://dx.doi.org/10.1155/2011/846263 |
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| _version_ | 1832566835809091584 |
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| author | Charnita M. Zeigler-Johnson Ann Tierney Timothy R. Rebbeck Andrew Rundle |
| author_facet | Charnita M. Zeigler-Johnson Ann Tierney Timothy R. Rebbeck Andrew Rundle |
| author_sort | Charnita M. Zeigler-Johnson |
| collection | DOAJ |
| description | Background. The goal of this paper was to examine neighborhood deprivation and prostate cancer severity.
Methods. We studied African American and Caucasian prostate cancer cases from the Pennsylvania State Cancer Registry. Census tract-level variables and deprivation scores were examined in relation to diagnosis stage, grade, and tumor aggressiveness.
Results. We observed associations of low SES with high Gleason score among African Americans residing in neighborhoods with low educational attainment (OR = 1.34, 95% CI = 1.13–1.60), high poverty (OR = 1.39, 95% CI = 1.15–1.67), low car ownership (OR = 1.46, 95% CI = 1.20–1.78), and higher percentage of residents on public assistance (OR = 1.32, 95% = 1.08–1.62). The highest quartile of neighborhood deprivation was also associated with high Gleason score. For both Caucasians and African Americans, the highest quartile of neighborhood deprivation was associated with high Gleason score at diagnosis (OR = 1.34, 95% CI = 1.19–1.52; OR = 1.71, 95% CI = 1.21–2.40, resp.).
Conclusion. Using a neighborhood deprivation index, we observed associations between high-grade prostate cancer and neighborhood deprivation in Caucasians and African-Americans. |
| format | Article |
| id | doaj-art-8395e9160cf24360b6441b922045dd7d |
| institution | Kabale University |
| issn | 2090-3111 2090-312X |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Prostate Cancer |
| spelling | doaj-art-8395e9160cf24360b6441b922045dd7d2025-02-03T01:03:03ZengWileyProstate Cancer2090-31112090-312X2011-01-01201110.1155/2011/846263846263Prostate Cancer Severity Associations with Neighborhood DeprivationCharnita M. Zeigler-Johnson0Ann Tierney1Timothy R. Rebbeck2Andrew Rundle3Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USACenter for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USACenter for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USAMailman School of Public Health, Columbia University, New York, NY 10027, USABackground. The goal of this paper was to examine neighborhood deprivation and prostate cancer severity. Methods. We studied African American and Caucasian prostate cancer cases from the Pennsylvania State Cancer Registry. Census tract-level variables and deprivation scores were examined in relation to diagnosis stage, grade, and tumor aggressiveness. Results. We observed associations of low SES with high Gleason score among African Americans residing in neighborhoods with low educational attainment (OR = 1.34, 95% CI = 1.13–1.60), high poverty (OR = 1.39, 95% CI = 1.15–1.67), low car ownership (OR = 1.46, 95% CI = 1.20–1.78), and higher percentage of residents on public assistance (OR = 1.32, 95% = 1.08–1.62). The highest quartile of neighborhood deprivation was also associated with high Gleason score. For both Caucasians and African Americans, the highest quartile of neighborhood deprivation was associated with high Gleason score at diagnosis (OR = 1.34, 95% CI = 1.19–1.52; OR = 1.71, 95% CI = 1.21–2.40, resp.). Conclusion. Using a neighborhood deprivation index, we observed associations between high-grade prostate cancer and neighborhood deprivation in Caucasians and African-Americans.http://dx.doi.org/10.1155/2011/846263 |
| spellingShingle | Charnita M. Zeigler-Johnson Ann Tierney Timothy R. Rebbeck Andrew Rundle Prostate Cancer Severity Associations with Neighborhood Deprivation Prostate Cancer |
| title | Prostate Cancer Severity Associations with Neighborhood Deprivation |
| title_full | Prostate Cancer Severity Associations with Neighborhood Deprivation |
| title_fullStr | Prostate Cancer Severity Associations with Neighborhood Deprivation |
| title_full_unstemmed | Prostate Cancer Severity Associations with Neighborhood Deprivation |
| title_short | Prostate Cancer Severity Associations with Neighborhood Deprivation |
| title_sort | prostate cancer severity associations with neighborhood deprivation |
| url | http://dx.doi.org/10.1155/2011/846263 |
| work_keys_str_mv | AT charnitamzeiglerjohnson prostatecancerseverityassociationswithneighborhooddeprivation AT anntierney prostatecancerseverityassociationswithneighborhooddeprivation AT timothyrrebbeck prostatecancerseverityassociationswithneighborhooddeprivation AT andrewrundle prostatecancerseverityassociationswithneighborhooddeprivation |