Protective Effects of Polydatin on Septic Lung Injury in Mice via Upregulation of HO-1
The present study was carried out to investigate the effects and mechanisms of polydatin (PD) in septic mice. The model of cecal ligation and puncture (CLP-)induced sepsis was employed. Pretreatment of mice with PD (15, 45, and 100 mg/kg) dose-dependently reduced sepsis-induced mortality and lung in...
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Main Authors: | Xiao-hui Li, Xia Gong, Li Zhang, Rong Jiang, Hong-zhong Li, Meng-jiao Wu, Jing-yuan Wan |
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Format: | Article |
Language: | English |
Published: |
Wiley
2013-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2013/354087 |
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