The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder Cancer

Non-muscle invasive bladder cancers are a heterogeneous group of cancers whose spectrum includes low grade Ta lesions and high-grade T1 lesions. Accurate staging and grading during initial evaluation and TUR ensures appropriate treatment and prevents the risk of understaging. TUR should be ideally...

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Main Authors: Alan M. Nieder, Murugesan Manoharan
Format: Article
Language:English
Published: Wiley 2006-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2006.405
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author Alan M. Nieder
Murugesan Manoharan
author_facet Alan M. Nieder
Murugesan Manoharan
author_sort Alan M. Nieder
collection DOAJ
description Non-muscle invasive bladder cancers are a heterogeneous group of cancers whose spectrum includes low grade Ta lesions and high-grade T1 lesions. Accurate staging and grading during initial evaluation and TUR ensures appropriate treatment and prevents the risk of understaging. TUR should be ideally performed under spinal anesthesia, with a continuous flow video resectoscope to maintain a stable bladder capacity, and a video monitor. The entire bladder must be visualized, with both 30- and 70-degree lenses, and all abnormal areas must be resected, with separate biopsies from each tumor's base. Repeat TUR is recommended for all high grade tumors and T1 tumors, especially if muscle was not present in the initial specimen. Immediate instillation of single dose chemotherapy agents following TUR is highly recommended to reduce the risk of tumor recurrences.
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spelling doaj-art-83790a6b0a2441fb8ab0a37692f2a8482025-02-03T05:51:21ZengWileyThe Scientific World Journal1537-744X2006-01-0162626263110.1100/tsw.2006.405The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder CancerAlan M. Nieder0Murugesan Manoharan1Department of Urology, University of Miami Miller School of Medicine, Miami, FL, USADepartment of Urology, University of Miami Miller School of Medicine, Miami, FL, USANon-muscle invasive bladder cancers are a heterogeneous group of cancers whose spectrum includes low grade Ta lesions and high-grade T1 lesions. Accurate staging and grading during initial evaluation and TUR ensures appropriate treatment and prevents the risk of understaging. TUR should be ideally performed under spinal anesthesia, with a continuous flow video resectoscope to maintain a stable bladder capacity, and a video monitor. The entire bladder must be visualized, with both 30- and 70-degree lenses, and all abnormal areas must be resected, with separate biopsies from each tumor's base. Repeat TUR is recommended for all high grade tumors and T1 tumors, especially if muscle was not present in the initial specimen. Immediate instillation of single dose chemotherapy agents following TUR is highly recommended to reduce the risk of tumor recurrences.http://dx.doi.org/10.1100/tsw.2006.405
spellingShingle Alan M. Nieder
Murugesan Manoharan
The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder Cancer
The Scientific World Journal
title The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder Cancer
title_full The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder Cancer
title_fullStr The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder Cancer
title_full_unstemmed The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder Cancer
title_short The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder Cancer
title_sort role of the surgeon and transurethral resection in the treatment of superficial bladder cancer
url http://dx.doi.org/10.1100/tsw.2006.405
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