Neural Plasticity in Common Forms of Chronic Headaches
Headaches are universal experiences and among the most common disorders. While headache may be physiological in the acute setting, it can become a pathological and persistent condition. The mechanisms underlying the transition from episodic to chronic pain have been the subject of intense study. Usi...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2015/205985 |
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| author | Tzu-Hsien Lai Ekaterina Protsenko Yu-Chen Cheng Marco L. Loggia Gianluca Coppola Wei-Ta Chen |
| author_facet | Tzu-Hsien Lai Ekaterina Protsenko Yu-Chen Cheng Marco L. Loggia Gianluca Coppola Wei-Ta Chen |
| author_sort | Tzu-Hsien Lai |
| collection | DOAJ |
| description | Headaches are universal experiences and among the most common disorders. While headache may be physiological in the acute setting, it can become a pathological and persistent condition. The mechanisms underlying the transition from episodic to chronic pain have been the subject of intense study. Using physiological and imaging methods, researchers have identified a number of different forms of neural plasticity associated with migraine and other headaches, including peripheral and central sensitization, and alterations in the endogenous mechanisms of pain modulation. While these changes have been proposed to contribute to headache and pain chronification, some findings are likely the results of repetitive noxious stimulation, such as atrophy of brain areas involved in pain perception and modulation. In this review, we provide a narrative overview of recent advances on the neuroimaging, electrophysiological and genetic aspects of neural plasticity associated with the most common forms of chronic headaches, including migraine, cluster headache, tension-type headache, and medication overuse headache. |
| format | Article |
| id | doaj-art-834be8979ca04ee6ac24a0752a7704e4 |
| institution | Kabale University |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-834be8979ca04ee6ac24a0752a7704e42025-02-03T01:12:04ZengWileyNeural Plasticity2090-59041687-54432015-01-01201510.1155/2015/205985205985Neural Plasticity in Common Forms of Chronic HeadachesTzu-Hsien Lai0Ekaterina Protsenko1Yu-Chen Cheng2Marco L. Loggia3Gianluca Coppola4Wei-Ta Chen5Department of Neurology, National Yang-Ming University School of Medicine, Taipei 112, TaiwanMGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USADepartment of Neurology, National Yang-Ming University School of Medicine, Taipei 112, TaiwanMGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USADepartment of Neurophysiology of Vision and Neurophthalmology, G.B. Bietti Foundation-IRCCS, 00198 Rome, ItalyDepartment of Neurology, National Yang-Ming University School of Medicine, Taipei 112, TaiwanHeadaches are universal experiences and among the most common disorders. While headache may be physiological in the acute setting, it can become a pathological and persistent condition. The mechanisms underlying the transition from episodic to chronic pain have been the subject of intense study. Using physiological and imaging methods, researchers have identified a number of different forms of neural plasticity associated with migraine and other headaches, including peripheral and central sensitization, and alterations in the endogenous mechanisms of pain modulation. While these changes have been proposed to contribute to headache and pain chronification, some findings are likely the results of repetitive noxious stimulation, such as atrophy of brain areas involved in pain perception and modulation. In this review, we provide a narrative overview of recent advances on the neuroimaging, electrophysiological and genetic aspects of neural plasticity associated with the most common forms of chronic headaches, including migraine, cluster headache, tension-type headache, and medication overuse headache.http://dx.doi.org/10.1155/2015/205985 |
| spellingShingle | Tzu-Hsien Lai Ekaterina Protsenko Yu-Chen Cheng Marco L. Loggia Gianluca Coppola Wei-Ta Chen Neural Plasticity in Common Forms of Chronic Headaches Neural Plasticity |
| title | Neural Plasticity in Common Forms of Chronic Headaches |
| title_full | Neural Plasticity in Common Forms of Chronic Headaches |
| title_fullStr | Neural Plasticity in Common Forms of Chronic Headaches |
| title_full_unstemmed | Neural Plasticity in Common Forms of Chronic Headaches |
| title_short | Neural Plasticity in Common Forms of Chronic Headaches |
| title_sort | neural plasticity in common forms of chronic headaches |
| url | http://dx.doi.org/10.1155/2015/205985 |
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