Development and validation of a genetic probability for venous thromboembolism
Background: Factor V Leiden (FVL) and prothrombin gene mutations (PGMs), as well as recently developed polygenic scores (PGSs), have been consistently associated with venous thromboembolism (VTE) risk in European ancestry populations. Objectives: This study aimed to develop an optimized risk-assessm...
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| Main Authors: | Zhuqing Shi, Ashley J. Mulford, Huy Tran, Michal Filipczak, Song Gao, Stevie Xie, Jason Lobel, Jun Wei, Andrew S. Rifkin, Annabelle Ashworth, Siqun Lilly Zheng, Clay Wiske, David Duggan, Brian T. Helfand, Arman Qamar, Alan R. Sanders, Alfonso J. Tafur, Jianfeng Xu |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-05-01
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| Series: | Research and Practice in Thrombosis and Haemostasis |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2475037925002006 |
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