Predictors of Acquired Perforating Dermatosis in Uremic Patients on Hemodialysis: A Case-Control Study
Objectives. The purpose of this study was to identify the predictors of acquired perforating dermatosis (APD) in patients on maintenance hemodialysis (HD). Methods. A case-control study was performed at our outpatient HD center between January 1, 2000 and March 31, 2011. Patients on HD with APD were...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2012/158075 |
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| author | Cheng-Hao Weng Ching-Chih Hu Shir-Hwa Ueng Chun-Chen Yu Chung-Yee Hui Ja-Liang Lin Chih-Wei Yang Cheng-Chieh Hung Ching-Wei Hsu Tzung-Hai Yen |
| author_facet | Cheng-Hao Weng Ching-Chih Hu Shir-Hwa Ueng Chun-Chen Yu Chung-Yee Hui Ja-Liang Lin Chih-Wei Yang Cheng-Chieh Hung Ching-Wei Hsu Tzung-Hai Yen |
| author_sort | Cheng-Hao Weng |
| collection | DOAJ |
| description | Objectives. The purpose of this study was to identify the predictors of acquired perforating dermatosis (APD) in patients on maintenance hemodialysis (HD). Methods. A case-control study was performed at our outpatient HD center between January 1, 2000 and March 31, 2011. Patients on HD with APD were matched (1 : 2) for gender and age with controls on HD. Conditional logistic regression was used to identify factors associated with APD. Results. A total of 19 patients with APD and 38 age and gender matched patients were enrolled in the study. Univariate logistic regression showed that APD was significantly associated with diabetes mellitus (DM), reduced levels of intact parathyroid hormone (iPTH) and albumin (Alb), reduced dialysis adequacy () and urea reduction rate (URR), and elevated levels of high-sensitivity C-reactive protein (hsCRP). Multivariate logistic regression identified reduced iPTH (hazard ratio (HR): 0.983; ) and Alb (HR: 0.099; ) and elevated hsCRP (HR: 1.210, ) as risk factors for APD. Conclusions. iPTH, hsCRP, and Alb are predictors for APD in HD patients. |
| format | Article |
| id | doaj-art-82484f9265f44918a3b1418817ed8ba2 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-82484f9265f44918a3b1418817ed8ba22025-02-03T01:21:30ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/158075158075Predictors of Acquired Perforating Dermatosis in Uremic Patients on Hemodialysis: A Case-Control StudyCheng-Hao Weng0Ching-Chih Hu1Shir-Hwa Ueng2Chun-Chen Yu3Chung-Yee Hui4Ja-Liang Lin5Chih-Wei Yang6Cheng-Chieh Hung7Ching-Wei Hsu8Tzung-Hai Yen9Department of Nephrology, Chang Gung Memorial Hospital, 5 Fu-Shin Street, Kwei-Shan, Taoyuan 333, TaiwanCollege of Medicine, Chang Gung University, Taoyuan 333, TaiwanCollege of Medicine, Chang Gung University, Taoyuan 333, TaiwanDepartment of Nephrology, Chang Gung Memorial Hospital, 5 Fu-Shin Street, Kwei-Shan, Taoyuan 333, TaiwanCollege of Medicine, Chang Gung University, Taoyuan 333, TaiwanDepartment of Nephrology, Chang Gung Memorial Hospital, 5 Fu-Shin Street, Kwei-Shan, Taoyuan 333, TaiwanDepartment of Nephrology, Chang Gung Memorial Hospital, 5 Fu-Shin Street, Kwei-Shan, Taoyuan 333, TaiwanDepartment of Nephrology, Chang Gung Memorial Hospital, 5 Fu-Shin Street, Kwei-Shan, Taoyuan 333, TaiwanDepartment of Nephrology, Chang Gung Memorial Hospital, 5 Fu-Shin Street, Kwei-Shan, Taoyuan 333, TaiwanDepartment of Nephrology, Chang Gung Memorial Hospital, 5 Fu-Shin Street, Kwei-Shan, Taoyuan 333, TaiwanObjectives. The purpose of this study was to identify the predictors of acquired perforating dermatosis (APD) in patients on maintenance hemodialysis (HD). Methods. A case-control study was performed at our outpatient HD center between January 1, 2000 and March 31, 2011. Patients on HD with APD were matched (1 : 2) for gender and age with controls on HD. Conditional logistic regression was used to identify factors associated with APD. Results. A total of 19 patients with APD and 38 age and gender matched patients were enrolled in the study. Univariate logistic regression showed that APD was significantly associated with diabetes mellitus (DM), reduced levels of intact parathyroid hormone (iPTH) and albumin (Alb), reduced dialysis adequacy () and urea reduction rate (URR), and elevated levels of high-sensitivity C-reactive protein (hsCRP). Multivariate logistic regression identified reduced iPTH (hazard ratio (HR): 0.983; ) and Alb (HR: 0.099; ) and elevated hsCRP (HR: 1.210, ) as risk factors for APD. Conclusions. iPTH, hsCRP, and Alb are predictors for APD in HD patients.http://dx.doi.org/10.1100/2012/158075 |
| spellingShingle | Cheng-Hao Weng Ching-Chih Hu Shir-Hwa Ueng Chun-Chen Yu Chung-Yee Hui Ja-Liang Lin Chih-Wei Yang Cheng-Chieh Hung Ching-Wei Hsu Tzung-Hai Yen Predictors of Acquired Perforating Dermatosis in Uremic Patients on Hemodialysis: A Case-Control Study The Scientific World Journal |
| title | Predictors of Acquired Perforating Dermatosis in Uremic Patients on Hemodialysis: A Case-Control Study |
| title_full | Predictors of Acquired Perforating Dermatosis in Uremic Patients on Hemodialysis: A Case-Control Study |
| title_fullStr | Predictors of Acquired Perforating Dermatosis in Uremic Patients on Hemodialysis: A Case-Control Study |
| title_full_unstemmed | Predictors of Acquired Perforating Dermatosis in Uremic Patients on Hemodialysis: A Case-Control Study |
| title_short | Predictors of Acquired Perforating Dermatosis in Uremic Patients on Hemodialysis: A Case-Control Study |
| title_sort | predictors of acquired perforating dermatosis in uremic patients on hemodialysis a case control study |
| url | http://dx.doi.org/10.1100/2012/158075 |
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