Radiofrequency Ablation for Treatment of Symptomatic Uterine Fibroids

The use of thermal energy-based systems to treat uterine fibroids has resulted in a plethora of devices that are less invasive and potentially as effective in reducing symptoms as traditional options such as myomectomy. Most thermal ablation devices involve hyperthermia (heating of tissue), which en...

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Main Authors: Siân Jones, Peter O'Donovan, David Toub
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Obstetrics and Gynecology International
Online Access:http://dx.doi.org/10.1155/2012/194839
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author Siân Jones
Peter O'Donovan
David Toub
author_facet Siân Jones
Peter O'Donovan
David Toub
author_sort Siân Jones
collection DOAJ
description The use of thermal energy-based systems to treat uterine fibroids has resulted in a plethora of devices that are less invasive and potentially as effective in reducing symptoms as traditional options such as myomectomy. Most thermal ablation devices involve hyperthermia (heating of tissue), which entails the conversion of an external electromagnetic or ultrasound waves into intracellular mechanical energy, generating heat. What has emerged from two decades of peer-reviewed research is the concept that hyperthermic fibroid ablation, regardless of the thermal energy source, can create large areas of necrosis within fibroids resulting in reductions in fibroid volume, associated symptoms and the need for reintervention. When a greater percentage of a fibroid's volume is ablated, symptomatic relief is more pronounced, quality of life increases, and it is more likely that such improvements will be durable. We review radiofrequency ablation (RFA), one modality of hyperthermic fibroid ablation.
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publishDate 2012-01-01
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series Obstetrics and Gynecology International
spelling doaj-art-822433126f7d499eb9ed6bf5ec4ae9092025-02-03T05:53:56ZengWileyObstetrics and Gynecology International1687-95891687-95972012-01-01201210.1155/2012/194839194839Radiofrequency Ablation for Treatment of Symptomatic Uterine FibroidsSiân Jones0Peter O'Donovan1David Toub2Department of Obstetrics and Gynaecology, Bradford Royal Infirmary, Duckworth Lane, Bradford BD9 6RJ, UKDepartment of Obstetrics and Gynaecology, Bradford Royal Infirmary, Duckworth Lane, Bradford BD9 6RJ, UKGynesonics, Inc., 604 Fifth Avenue, Suite D, Redwood City, CA 94063, USAThe use of thermal energy-based systems to treat uterine fibroids has resulted in a plethora of devices that are less invasive and potentially as effective in reducing symptoms as traditional options such as myomectomy. Most thermal ablation devices involve hyperthermia (heating of tissue), which entails the conversion of an external electromagnetic or ultrasound waves into intracellular mechanical energy, generating heat. What has emerged from two decades of peer-reviewed research is the concept that hyperthermic fibroid ablation, regardless of the thermal energy source, can create large areas of necrosis within fibroids resulting in reductions in fibroid volume, associated symptoms and the need for reintervention. When a greater percentage of a fibroid's volume is ablated, symptomatic relief is more pronounced, quality of life increases, and it is more likely that such improvements will be durable. We review radiofrequency ablation (RFA), one modality of hyperthermic fibroid ablation.http://dx.doi.org/10.1155/2012/194839
spellingShingle Siân Jones
Peter O'Donovan
David Toub
Radiofrequency Ablation for Treatment of Symptomatic Uterine Fibroids
Obstetrics and Gynecology International
title Radiofrequency Ablation for Treatment of Symptomatic Uterine Fibroids
title_full Radiofrequency Ablation for Treatment of Symptomatic Uterine Fibroids
title_fullStr Radiofrequency Ablation for Treatment of Symptomatic Uterine Fibroids
title_full_unstemmed Radiofrequency Ablation for Treatment of Symptomatic Uterine Fibroids
title_short Radiofrequency Ablation for Treatment of Symptomatic Uterine Fibroids
title_sort radiofrequency ablation for treatment of symptomatic uterine fibroids
url http://dx.doi.org/10.1155/2012/194839
work_keys_str_mv AT sianjones radiofrequencyablationfortreatmentofsymptomaticuterinefibroids
AT peterodonovan radiofrequencyablationfortreatmentofsymptomaticuterinefibroids
AT davidtoub radiofrequencyablationfortreatmentofsymptomaticuterinefibroids