Effect of metformin on the neuronal morphology of frontal cortex and hippocampal regions in lipopolysaccharide induced neuroinflammation in male Wistar rats

Background: Neuroinflammation in the frontal cortex and hippocampus is the key contributor in the pathogenesis of neurodegenerative diseases. Lipopolysaccharide (LPS) is a bacterial endotoxin (E-coli phenol extract) used to induce the neuroinflammation in animal models. Our study is aimed to study t...

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Bibliographic Details
Main Authors: Vandana Blossom, Sheetal D. Ullal, Rajalakshmi Rai, Amit Massand, Chettiar Ganesh Kumar, Teresa Joy, Melisha Michael D souza, B.V. Murlimanju
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Translational Research in Anatomy
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214854X2400089X
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