Alkaloids in Processed Rhizoma Corydalis and Crude Rhizoma Corydalis Analyzed by GC/MS
The alkaloids in the processed Rhizoma Corydalis and the crude Rhizoma Corydalis were qualitatively and semiquantitatively analyzed using gas chromatography-mass spectrometry (GC/MS) method. The processing herb drug procedure was carried out according to the standard method of Chinese Pharmacopoeia....
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Journal of Analytical Methods in Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2014/281342 |
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| author | Zhifeng Guo Ru Cai Huidan Su Yunlong Li |
| author_facet | Zhifeng Guo Ru Cai Huidan Su Yunlong Li |
| author_sort | Zhifeng Guo |
| collection | DOAJ |
| description | The alkaloids in the processed Rhizoma Corydalis and the crude Rhizoma Corydalis were qualitatively and semiquantitatively analyzed using gas chromatography-mass spectrometry (GC/MS) method. The processing herb drug procedure was carried out according to the standard method of Chinese Pharmacopoeia. The samples were extracted using Soxhlet extractor with different solvents: methanol and acetone. The extraction effect on different solvents was investigated. The results showed that 11 kinds of alkaloids were identified from the crude Rhizoma Corydalis and only two were from the processed Rhizoma Corydalis. A total of 13 kinds of alkaloids were all based on two backbones. The alkaloids in the processed sample were less than those in the crude Rhizoma Corydalis significantly, while almost the corydaline has been changed in conformation after the sample had undergone processing, which provided support for the conclusion of reducing toxicity when the herbal medicine having been undergone a traditional drugs treatment process. |
| format | Article |
| id | doaj-art-8205e8b7694b48dd9fd2e7b8d92987a3 |
| institution | Kabale University |
| issn | 2090-8865 2090-8873 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Analytical Methods in Chemistry |
| spelling | doaj-art-8205e8b7694b48dd9fd2e7b8d92987a32025-02-03T06:44:26ZengWileyJournal of Analytical Methods in Chemistry2090-88652090-88732014-01-01201410.1155/2014/281342281342Alkaloids in Processed Rhizoma Corydalis and Crude Rhizoma Corydalis Analyzed by GC/MSZhifeng Guo0Ru Cai1Huidan Su2Yunlong Li3Key Laboratory of Medical Chemistry and Molecular Diagnosis, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, ChinaKey Laboratory of Medical Chemistry and Molecular Diagnosis, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, ChinaKey Laboratory of Medical Chemistry and Molecular Diagnosis, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, ChinaKey Laboratory of Medical Chemistry and Molecular Diagnosis, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, ChinaThe alkaloids in the processed Rhizoma Corydalis and the crude Rhizoma Corydalis were qualitatively and semiquantitatively analyzed using gas chromatography-mass spectrometry (GC/MS) method. The processing herb drug procedure was carried out according to the standard method of Chinese Pharmacopoeia. The samples were extracted using Soxhlet extractor with different solvents: methanol and acetone. The extraction effect on different solvents was investigated. The results showed that 11 kinds of alkaloids were identified from the crude Rhizoma Corydalis and only two were from the processed Rhizoma Corydalis. A total of 13 kinds of alkaloids were all based on two backbones. The alkaloids in the processed sample were less than those in the crude Rhizoma Corydalis significantly, while almost the corydaline has been changed in conformation after the sample had undergone processing, which provided support for the conclusion of reducing toxicity when the herbal medicine having been undergone a traditional drugs treatment process.http://dx.doi.org/10.1155/2014/281342 |
| spellingShingle | Zhifeng Guo Ru Cai Huidan Su Yunlong Li Alkaloids in Processed Rhizoma Corydalis and Crude Rhizoma Corydalis Analyzed by GC/MS Journal of Analytical Methods in Chemistry |
| title | Alkaloids in Processed Rhizoma Corydalis and Crude Rhizoma Corydalis Analyzed by GC/MS |
| title_full | Alkaloids in Processed Rhizoma Corydalis and Crude Rhizoma Corydalis Analyzed by GC/MS |
| title_fullStr | Alkaloids in Processed Rhizoma Corydalis and Crude Rhizoma Corydalis Analyzed by GC/MS |
| title_full_unstemmed | Alkaloids in Processed Rhizoma Corydalis and Crude Rhizoma Corydalis Analyzed by GC/MS |
| title_short | Alkaloids in Processed Rhizoma Corydalis and Crude Rhizoma Corydalis Analyzed by GC/MS |
| title_sort | alkaloids in processed rhizoma corydalis and crude rhizoma corydalis analyzed by gc ms |
| url | http://dx.doi.org/10.1155/2014/281342 |
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