Trabeculectomy with Healaflow versus Trabeculectomy for the Treatment of Glaucoma: A Case-Control Study

Purpose. To compare the outcomes of trabeculectomy with and without Healaflow (Anteis S.A, Geneva, Switzerland), a high molecular weight viscoelastic gel, in patients requiring glaucoma surgery. Methods. This was a retrospective, comparative, interventional case-control study. Forty patients forme...

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Main Authors: Dimitris Papaconstantinou, Andreas Diagourtas, Petros Petrou, Alexandros Rouvas, Athanasios Vergados, Chryssanthi Koutsandrea, Ilias Georgalas
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2015/836269
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author Dimitris Papaconstantinou
Andreas Diagourtas
Petros Petrou
Alexandros Rouvas
Athanasios Vergados
Chryssanthi Koutsandrea
Ilias Georgalas
author_facet Dimitris Papaconstantinou
Andreas Diagourtas
Petros Petrou
Alexandros Rouvas
Athanasios Vergados
Chryssanthi Koutsandrea
Ilias Georgalas
author_sort Dimitris Papaconstantinou
collection DOAJ
description Purpose. To compare the outcomes of trabeculectomy with and without Healaflow (Anteis S.A, Geneva, Switzerland), a high molecular weight viscoelastic gel, in patients requiring glaucoma surgery. Methods. This was a retrospective, comparative, interventional case-control study. Forty patients formed two matched study groups and were analyzed (trabeculectomy alone (control) versus trabeculectomy with Healaflow (study)). Results. The postoperative levels of mean IOP were statistically significantly lower P<0.05 than preoperatively in both groups, for all time intervals. There was no statistical difference, at the end of the follow-up period, between the two groups in the mean values of the IOP (14.9 ± 3.2 mmHg for the study group versus 14.8 ± 3.3 mmHg for the control group). The number of antiglaucoma drugs used in the study group was reduced from a preoperative mean of 3.4 ± 0.75 to a 6-month postoperative mean of 0.6 ± 0.8 P<0.001 and in the control group from 3.6 ± 0.59 to 0.55 ± 0.9 P<0.001. Conclusions. Although trabeculectomy with Healaflow appears to be a safe procedure, we failed to identify any significant advantages in the use of Healaflow when compared with trabeculectomy alone, at the end of the 6-month follow-up period.
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spelling doaj-art-81b7cb27cc7648cba55248890464e6672025-02-03T05:45:41ZengWileyJournal of Ophthalmology2090-004X2090-00582015-01-01201510.1155/2015/836269836269Trabeculectomy with Healaflow versus Trabeculectomy for the Treatment of Glaucoma: A Case-Control StudyDimitris Papaconstantinou0Andreas Diagourtas1Petros Petrou2Alexandros Rouvas3Athanasios Vergados4Chryssanthi Koutsandrea5Ilias Georgalas6Department of Ophthalmology, “G. Gennimatas” Hospital, University of Athens, Mesogeion Avenue, 11527 Athens, GreeceDepartment of Ophthalmology, “G. Gennimatas” Hospital, University of Athens, Mesogeion Avenue, 11527 Athens, GreeceDepartment of Ophthalmology, “G. Gennimatas” Hospital, University of Athens, Mesogeion Avenue, 11527 Athens, GreeceDepartment of Ophthalmology, “G. Gennimatas” Hospital, University of Athens, Mesogeion Avenue, 11527 Athens, GreeceDepartment of Ophthalmology, “G. Gennimatas” Hospital, University of Athens, Mesogeion Avenue, 11527 Athens, GreeceDepartment of Ophthalmology, “G. Gennimatas” Hospital, University of Athens, Mesogeion Avenue, 11527 Athens, GreeceDepartment of Ophthalmology, “G. Gennimatas” Hospital, University of Athens, Mesogeion Avenue, 11527 Athens, GreecePurpose. To compare the outcomes of trabeculectomy with and without Healaflow (Anteis S.A, Geneva, Switzerland), a high molecular weight viscoelastic gel, in patients requiring glaucoma surgery. Methods. This was a retrospective, comparative, interventional case-control study. Forty patients formed two matched study groups and were analyzed (trabeculectomy alone (control) versus trabeculectomy with Healaflow (study)). Results. The postoperative levels of mean IOP were statistically significantly lower P<0.05 than preoperatively in both groups, for all time intervals. There was no statistical difference, at the end of the follow-up period, between the two groups in the mean values of the IOP (14.9 ± 3.2 mmHg for the study group versus 14.8 ± 3.3 mmHg for the control group). The number of antiglaucoma drugs used in the study group was reduced from a preoperative mean of 3.4 ± 0.75 to a 6-month postoperative mean of 0.6 ± 0.8 P<0.001 and in the control group from 3.6 ± 0.59 to 0.55 ± 0.9 P<0.001. Conclusions. Although trabeculectomy with Healaflow appears to be a safe procedure, we failed to identify any significant advantages in the use of Healaflow when compared with trabeculectomy alone, at the end of the 6-month follow-up period.http://dx.doi.org/10.1155/2015/836269
spellingShingle Dimitris Papaconstantinou
Andreas Diagourtas
Petros Petrou
Alexandros Rouvas
Athanasios Vergados
Chryssanthi Koutsandrea
Ilias Georgalas
Trabeculectomy with Healaflow versus Trabeculectomy for the Treatment of Glaucoma: A Case-Control Study
Journal of Ophthalmology
title Trabeculectomy with Healaflow versus Trabeculectomy for the Treatment of Glaucoma: A Case-Control Study
title_full Trabeculectomy with Healaflow versus Trabeculectomy for the Treatment of Glaucoma: A Case-Control Study
title_fullStr Trabeculectomy with Healaflow versus Trabeculectomy for the Treatment of Glaucoma: A Case-Control Study
title_full_unstemmed Trabeculectomy with Healaflow versus Trabeculectomy for the Treatment of Glaucoma: A Case-Control Study
title_short Trabeculectomy with Healaflow versus Trabeculectomy for the Treatment of Glaucoma: A Case-Control Study
title_sort trabeculectomy with healaflow versus trabeculectomy for the treatment of glaucoma a case control study
url http://dx.doi.org/10.1155/2015/836269
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