Basidiobolomycosis Simulating a Mycobacterium ulcerans Infection in a Togolese Rural Child
Background. Basidiobolomycosis is a deep mycosis which preferentially affects rural young people in tropical countries. We report an atypical case, with multiple ulcers, simulating a Buruli ulcer. Case Report. A 5-year-old boy, living in a rural area, was seen for ulcers on the buttocks and at the b...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Dermatological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2017/6905783 |
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| author | Bayaki Saka Waguena Gnassingbe Garba Mahamadou Sefako Akakpo Julienne Teclessou Aurel Abilogun-Chokki Abas Mouhari-Toure Koussake Kombate Palokinam Pitché |
| author_facet | Bayaki Saka Waguena Gnassingbe Garba Mahamadou Sefako Akakpo Julienne Teclessou Aurel Abilogun-Chokki Abas Mouhari-Toure Koussake Kombate Palokinam Pitché |
| author_sort | Bayaki Saka |
| collection | DOAJ |
| description | Background. Basidiobolomycosis is a deep mycosis which preferentially affects rural young people in tropical countries. We report an atypical case, with multiple ulcers, simulating a Buruli ulcer. Case Report. A 5-year-old boy, living in a rural area, was seen for ulcers on the buttocks and at the back and right flank that had been in progress for 4 months. On examination, we found an infiltrated plaque with sharp edges, little painful, located on the buttocks, back, and the right flank. On this plaque, there were multiple ulcers with polycyclic contours and fibrinous bottom. There were inguinal inflammatory lymph nodes. The patient had an altered general condition. Examination of other organs was normal. The diagnosis of Buruli ulcer was evoked first; the search for Mycobacterium ulcerans by polymerase chain reaction was negative. Histology test performed revealed hypodermic granulomatous inflammation with predominant macrophage and eosinophils. The mycological culture was not done. The child was treated successfully with ketoconazole (10 mg/kg/day) during eight weeks. Discussion. Our observation shows great clinical and epidemiological similarities between basidiobolomycosis and Buruli ulcer. It confirms the efficacy of ketoconazole in severe basidiobolomycosis infection with alteration of general condition. Histopathology is very important for differential diagnosis between these two diseases. |
| format | Article |
| id | doaj-art-8180276c33a349df8bcde318e76a96bb |
| institution | Kabale University |
| issn | 2090-6463 2090-6471 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dermatological Medicine |
| spelling | doaj-art-8180276c33a349df8bcde318e76a96bb2025-02-03T05:57:36ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712017-01-01201710.1155/2017/69057836905783Basidiobolomycosis Simulating a Mycobacterium ulcerans Infection in a Togolese Rural ChildBayaki Saka0Waguena Gnassingbe1Garba Mahamadou2Sefako Akakpo3Julienne Teclessou4Aurel Abilogun-Chokki5Abas Mouhari-Toure6Koussake Kombate7Palokinam Pitché8Service de Dermatologie et IST, CHU Sylvanus Olympio, Université de Lomé, Lomé, TogoService de Dermatologie et IST, CHU Sylvanus Olympio, Université de Lomé, Lomé, TogoService de Dermatologie et IST, CHU Sylvanus Olympio, Université de Lomé, Lomé, TogoService de Dermatologie et IST, CHU Sylvanus Olympio, Université de Lomé, Lomé, TogoService de Dermatologie et IST, CHU Campus de Lomé, Université de Lomé, Lomé, TogoService de Dermatologie et IST, CHU Sylvanus Olympio, Université de Lomé, Lomé, TogoService de Dermatologie et IST, CHU de Kara, Université de Kara, Kara, TogoService de Dermatologie et IST, CHU Campus de Lomé, Université de Lomé, Lomé, TogoService de Dermatologie et IST, CHU Sylvanus Olympio, Université de Lomé, Lomé, TogoBackground. Basidiobolomycosis is a deep mycosis which preferentially affects rural young people in tropical countries. We report an atypical case, with multiple ulcers, simulating a Buruli ulcer. Case Report. A 5-year-old boy, living in a rural area, was seen for ulcers on the buttocks and at the back and right flank that had been in progress for 4 months. On examination, we found an infiltrated plaque with sharp edges, little painful, located on the buttocks, back, and the right flank. On this plaque, there were multiple ulcers with polycyclic contours and fibrinous bottom. There were inguinal inflammatory lymph nodes. The patient had an altered general condition. Examination of other organs was normal. The diagnosis of Buruli ulcer was evoked first; the search for Mycobacterium ulcerans by polymerase chain reaction was negative. Histology test performed revealed hypodermic granulomatous inflammation with predominant macrophage and eosinophils. The mycological culture was not done. The child was treated successfully with ketoconazole (10 mg/kg/day) during eight weeks. Discussion. Our observation shows great clinical and epidemiological similarities between basidiobolomycosis and Buruli ulcer. It confirms the efficacy of ketoconazole in severe basidiobolomycosis infection with alteration of general condition. Histopathology is very important for differential diagnosis between these two diseases.http://dx.doi.org/10.1155/2017/6905783 |
| spellingShingle | Bayaki Saka Waguena Gnassingbe Garba Mahamadou Sefako Akakpo Julienne Teclessou Aurel Abilogun-Chokki Abas Mouhari-Toure Koussake Kombate Palokinam Pitché Basidiobolomycosis Simulating a Mycobacterium ulcerans Infection in a Togolese Rural Child Case Reports in Dermatological Medicine |
| title | Basidiobolomycosis Simulating a Mycobacterium ulcerans Infection in a Togolese Rural Child |
| title_full | Basidiobolomycosis Simulating a Mycobacterium ulcerans Infection in a Togolese Rural Child |
| title_fullStr | Basidiobolomycosis Simulating a Mycobacterium ulcerans Infection in a Togolese Rural Child |
| title_full_unstemmed | Basidiobolomycosis Simulating a Mycobacterium ulcerans Infection in a Togolese Rural Child |
| title_short | Basidiobolomycosis Simulating a Mycobacterium ulcerans Infection in a Togolese Rural Child |
| title_sort | basidiobolomycosis simulating a mycobacterium ulcerans infection in a togolese rural child |
| url | http://dx.doi.org/10.1155/2017/6905783 |
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