Sarcoidosis and Its Splenic Wonder: A Rare Case of Isolated Splenic Sarcoidosis
Sarcoidosis is a systemic granulomatous disease of unknown etiology characterized by presence of noncaseating granulomas in the involved organs. The pulmonary interstitium is most commonly affected but extrapulmonary involvement can occur in almost any other organ system. Such an involvement can occ...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/4628439 |
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| author | Khushali Jhaveri Abhay Vakil Salim R. Surani |
| author_facet | Khushali Jhaveri Abhay Vakil Salim R. Surani |
| author_sort | Khushali Jhaveri |
| collection | DOAJ |
| description | Sarcoidosis is a systemic granulomatous disease of unknown etiology characterized by presence of noncaseating granulomas in the involved organs. The pulmonary interstitium is most commonly affected but extrapulmonary involvement can occur in almost any other organ system. Such an involvement can occur with or without the presence of pulmonary involvement, but isolated extrapulmonary involvement has been noted only in around 10% of cases. Isolated splenomegaly is very rare and an uncommon presentation of sarcoidosis. It is clinically challenging because of the extensive differential diagnosis. Among the many considerations are hematologic malignancies, primary splenic or metastatic tumors, infiltrative disorders, inflammatory disorders, and infections. We hereby discuss an interesting case of a 40-year-old female with isolated splenic sarcoidosis. |
| format | Article |
| id | doaj-art-81304a359a79493bb1f71ace77eb05f4 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-81304a359a79493bb1f71ace77eb05f42025-02-03T07:24:52ZengWileyCase Reports in Medicine1687-96271687-96352018-01-01201810.1155/2018/46284394628439Sarcoidosis and Its Splenic Wonder: A Rare Case of Isolated Splenic SarcoidosisKhushali Jhaveri0Abhay Vakil1Salim R. Surani2Department of Internal Medicine, Georgetown University Washington Hospital Center, Washington, DC, USAUniversity of North Texas, Denton, TX, USATexas A&M University, College Station, TX, USASarcoidosis is a systemic granulomatous disease of unknown etiology characterized by presence of noncaseating granulomas in the involved organs. The pulmonary interstitium is most commonly affected but extrapulmonary involvement can occur in almost any other organ system. Such an involvement can occur with or without the presence of pulmonary involvement, but isolated extrapulmonary involvement has been noted only in around 10% of cases. Isolated splenomegaly is very rare and an uncommon presentation of sarcoidosis. It is clinically challenging because of the extensive differential diagnosis. Among the many considerations are hematologic malignancies, primary splenic or metastatic tumors, infiltrative disorders, inflammatory disorders, and infections. We hereby discuss an interesting case of a 40-year-old female with isolated splenic sarcoidosis.http://dx.doi.org/10.1155/2018/4628439 |
| spellingShingle | Khushali Jhaveri Abhay Vakil Salim R. Surani Sarcoidosis and Its Splenic Wonder: A Rare Case of Isolated Splenic Sarcoidosis Case Reports in Medicine |
| title | Sarcoidosis and Its Splenic Wonder: A Rare Case of Isolated Splenic Sarcoidosis |
| title_full | Sarcoidosis and Its Splenic Wonder: A Rare Case of Isolated Splenic Sarcoidosis |
| title_fullStr | Sarcoidosis and Its Splenic Wonder: A Rare Case of Isolated Splenic Sarcoidosis |
| title_full_unstemmed | Sarcoidosis and Its Splenic Wonder: A Rare Case of Isolated Splenic Sarcoidosis |
| title_short | Sarcoidosis and Its Splenic Wonder: A Rare Case of Isolated Splenic Sarcoidosis |
| title_sort | sarcoidosis and its splenic wonder a rare case of isolated splenic sarcoidosis |
| url | http://dx.doi.org/10.1155/2018/4628439 |
| work_keys_str_mv | AT khushalijhaveri sarcoidosisanditssplenicwonderararecaseofisolatedsplenicsarcoidosis AT abhayvakil sarcoidosisanditssplenicwonderararecaseofisolatedsplenicsarcoidosis AT salimrsurani sarcoidosisanditssplenicwonderararecaseofisolatedsplenicsarcoidosis |