Social jetlag elicits fatty liver via perturbed circulating prolactin rhythm-mediated circadian remodeling of hepatic lipid metabolism

Social jetlag elicits fatty liver via perturbed circulating prolactin rhythm-mediated circadian remodeling of hepatic lipid metabolism

Abstract Background The prevalence of circadian misalignment, particularly social jetlag (SJL), contributes significantly to the epidemic of metabolic disorders. However, the precise impact of SJL on the liver has remained poorly elucidated. Methods The rhythmicity of circulating prolactin (PRL) was...

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Bibliographic Details
Main Authors: Peng-Zi Zhang, Ying-Huan Shi, Yu-Xin Guo, Ya-Yuan Li, Hong-Li Yin, Tian-Yu Wu, Ye Zhu, Jia-Xuan Jiang, Yan Bi
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Military Medical Research
Subjects:
Social jetlag
Prolactin
Circadian rhythm
Metabolic dysfunction-associated steatotic liver disease (MASLD)
Online Access:https://doi.org/10.1186/s40779-025-00609-z
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