Cefmetazole, flomoxef, and meropenem are effective against planktonic cells but not biofilms of extended-spectrum β-lactamase-producing Escherichia coli

Cefmetazole, flomoxef, and meropenem are effective against planktonic cells but not biofilms of extended-spectrum β-lactamase-producing Escherichia coli

Abstract Background Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli is a potential  public health threat through its spread into the environment. Cefmetazole (CMZ) and flomoxef (FMOX) are highly effective alternatives to meropenem (MEM) for the management of ESBL-producing E. coli in...

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Bibliographic Details
Main Authors: Nami Hatayama, Yoshinori Sato, Rika Tahira, Toki Hori, Shigeru Tansho-Nagakawa, Yasuo Ono, Yusuke Yoshino
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Microbiology
Subjects:
Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli
Biofilms
Cefmetazole
Flomoxef
Meropenem
Inhibitory and bactericidal effects of antibiotics
Online Access:https://doi.org/10.1186/s12866-025-04088-z
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