Polydatin-Induced Shift of Redox Balance and Its Anti-Cancer Impact on Human Osteosarcoma Cells

Polydatin-Induced Shift of Redox Balance and Its Anti-Cancer Impact on Human Osteosarcoma Cells

Cancer cells demonstrate remarkable resilience by adapting to oxidative stress and undergoing metabolic reprogramming, making oxidative stress a critical target for cancer therapy. This study explores, for the first time, the redox-dependent anticancer effects of Polydatin (PD), a glucoside derivati...

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Bibliographic Details
Main Authors: Alessio Cimmino, Magda Gioia, Maria Elisabetta Clementi, Isabella Faraoni, Stefano Marini, Chiara Ciaccio
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Current Issues in Molecular Biology
Subjects:
Osteosarcoma
Polydatin
ROS
GSH
ferroptosis
hypoxia
Online Access:https://www.mdpi.com/1467-3045/47/1/21
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