The results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2

Purpose: To compare the results of laser treatment and intravitreal ranibizumab injections in patients with DME consistent with the level of VEGF A in tear fluid.Methods: The progress of visual acuity, retinal thickness and light sensivity after laser treatment and ranibizumab intravitreal injection...

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Main Authors: I. V. Vorobieva, E. V. Parfenova, D. A. Merkushenkova, P. I. Makarevich, V. I. Alekhnovich
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2014-07-01
Series:Oftalʹmologiâ
Subjects:
Online Access:https://www.ophthalmojournal.com/opht/article/view/77
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author I. V. Vorobieva
E. V. Parfenova
D. A. Merkushenkova
P. I. Makarevich
V. I. Alekhnovich
author_facet I. V. Vorobieva
E. V. Parfenova
D. A. Merkushenkova
P. I. Makarevich
V. I. Alekhnovich
author_sort I. V. Vorobieva
collection DOAJ
description Purpose: To compare the results of laser treatment and intravitreal ranibizumab injections in patients with DME consistent with the level of VEGF A in tear fluid.Methods: The progress of visual acuity, retinal thickness and light sensivity after laser treatment and ranibizumab intravitreal injection has been assessed.Results: One month after the treatment the main effect of laser was the decrease of retinal thickness, whereas after ranibizumab — the increase of visual acuity. The significant decrease of VEGF A level in tear fluid was found only in ranibizumab group.Conclusion: Laser treatment of DME leads to permanent retinal thickness decrease and insignificant functional improvement in comparison with ranibizumab IV injection, which leads to temporary morphological and functional improvement.
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publishDate 2014-07-01
publisher Ophthalmology Publishing Group
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series Oftalʹmologiâ
spelling doaj-art-80e8db273a2a47249700a88d76754a492025-08-20T03:22:12ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452014-07-01102444910.18008/1816-5095-2013-2-44-4977The results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2I. V. Vorobieva0E. V. Parfenova1D. A. Merkushenkova2P. I. Makarevich3V. I. Alekhnovich4ГБОУ ДПО РМАПО Минздрава РоссииГБОУ ДПО РМАПО Минздрава РоссииФГБОУ ВПО МГУ им. М. В. ЛомоносоваФГБОУ ВПО МГУ им. М. В. ЛомоносоваФГБОУ ВПО МГТУ им. Н. Э. БауманаPurpose: To compare the results of laser treatment and intravitreal ranibizumab injections in patients with DME consistent with the level of VEGF A in tear fluid.Methods: The progress of visual acuity, retinal thickness and light sensivity after laser treatment and ranibizumab intravitreal injection has been assessed.Results: One month after the treatment the main effect of laser was the decrease of retinal thickness, whereas after ranibizumab — the increase of visual acuity. The significant decrease of VEGF A level in tear fluid was found only in ranibizumab group.Conclusion: Laser treatment of DME leads to permanent retinal thickness decrease and insignificant functional improvement in comparison with ranibizumab IV injection, which leads to temporary morphological and functional improvement.https://www.ophthalmojournal.com/opht/article/view/77dmeantiangiogenic treatmentvegf alaserranibizumab
spellingShingle I. V. Vorobieva
E. V. Parfenova
D. A. Merkushenkova
P. I. Makarevich
V. I. Alekhnovich
The results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2
Oftalʹmologiâ
dme
antiangiogenic treatment
vegf a
laser
ranibizumab
title The results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2
title_full The results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2
title_fullStr The results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2
title_full_unstemmed The results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2
title_short The results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2
title_sort results of comparative analysis of angiogenic and laser therapy for diabetic macular edema in diabetes type 2
topic dme
antiangiogenic treatment
vegf a
laser
ranibizumab
url https://www.ophthalmojournal.com/opht/article/view/77
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