Citrullinated Autoantigen–Specific T and B Lymphocytes in Rheumatoid Arthritis: Focus on Follicular T Helper Cells and Expansion by Coculture

Citrullinated Autoantigen–Specific T and B Lymphocytes in Rheumatoid Arthritis: Focus on Follicular T Helper Cells and Expansion by Coculture

Objective Rheumatoid arthritis (RA) is characterized by circulating anti–cyclic citrullinated peptide (CCP) autoantibodies (ACPAs), resulting in inflammation of the joints and other organs. We have established novel assays to assess immune cell subpopulations, including citrullinated antigen–specifi...

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Bibliographic Details
Main Authors: Tim Ammon, Julia Zeiträg, Vanessa Mayr, Manuela Benedicic, Hans‐Peter Holthoff, Martin Ungerer
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:ACR Open Rheumatology
Online Access:https://doi.org/10.1002/acr2.11785
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