Competitive exclusion and coexistence in a two-strain pathogen model with diffusion

We consider a two-strain pathogen model described by a system of reaction-diffusion equations. We define a basic reproduction number $R_0$ and show that when the model parameters are constant (spatially homogeneous), if $R_0 >1$ then one strain will outcompete the other strain and drive it to ex...

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Bibliographic Details
Main Authors: Azmy S. Ackleh, Keng Deng, Yixiang Wu
Format: Article
Language:English
Published: AIMS Press 2015-09-01
Series:Mathematical Biosciences and Engineering
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Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2016.13.1
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Summary:We consider a two-strain pathogen model described by a system of reaction-diffusion equations. We define a basic reproduction number $R_0$ and show that when the model parameters are constant (spatially homogeneous), if $R_0 >1$ then one strain will outcompete the other strain and drive it to extinction, but if $R_0 \le 1$ then the disease-free equilibrium is globally attractive. When we assume that the diffusion rates are equal while the transmission and recovery rates are heterogeneous, then there are two possible outcomes under the condition $R_0 >1$: 1) Competitive exclusion where one strain dies out. 2) Coexistence between the two strains. Thus, spatial heterogeneity promotes coexistence.
ISSN:1551-0018