Therapeutic effects of extended daily hemofiltration and intermittent hemodialysis for systemic inflammatory response syndrome with acute kidney injury

Objective To compare the effect of extended daily hemofiltration(EDHF) and intermittent hemodialysis(IHD) for patients with systemic inflammatory response syndrome(SIRS) and acute kidney injury(AKI).Methods Forty patients with SIRS and AKI in Yangpu Hospital from Jan.2010 to May 2013 were collected...

Full description

Saved in:
Bibliographic Details
Main Authors: FENG Xue-fang, ZHOU Rong, XU Ya-hong, ZHANG Yun, CHEN Ming-dong, SHEN Jie
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2016-01-01
Series:Linchuang shenzangbing zazhi
Subjects:
Online Access:http://www.lcszb.com/thesisDetails?columnId=57918335&Fpath=home&index=0
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849313234099634176
author FENG Xue-fang
ZHOU Rong
XU Ya-hong
ZHANG Yun
CHEN Ming-dong
SHEN Jie
author_facet FENG Xue-fang
ZHOU Rong
XU Ya-hong
ZHANG Yun
CHEN Ming-dong
SHEN Jie
author_sort FENG Xue-fang
collection DOAJ
description Objective To compare the effect of extended daily hemofiltration(EDHF) and intermittent hemodialysis(IHD) for patients with systemic inflammatory response syndrome(SIRS) and acute kidney injury(AKI).Methods Forty patients with SIRS and AKI in Yangpu Hospital from Jan.2010 to May 2013 were collected prospectively.Patients were given EDHF or IHD in addition to the routine management The following endpoints were measured and compared between two groups:the baseline level,the progression of disease(including mortality rate in hospital,kidney survival rate,length and expenses of hospitalization,and the incidence of disease complications),the serum BUN and creatinine levels.Results(1) 17(85%) patients in the EDHF group got through the acute phase of disease and 3(15%) patients did not survive,while in the IHD group 15(75%) patients survived and 5(25%) patients died.No significant difference in survival rate was found between the two groups.Fourteen patients(70%) in the EDHF group got rid of dialysis,while in the IHD group,9out of 20(45%) did There was also no significant difference in kidney survival rate between the two groups.The average days of hospitalization in the EDHF group was(32.6 ± 8.6) days,significantly shorter than in the IHD group(39.2 ± 11.5) days(P<0.05),but the expenses of hospitalization was comparable between two groups(P>0.05).(2) The creatinine level on the 5th day after hemodialysis in the EDHF group was(243.5±92.8) μmol/L,significantly lower than that in the IHD group(363.8 ± 209.0) μmol/L(P<0.05).Conclusions In management of SIRS with AKI,it seemed that the EDHF lowered the mortality rate in hospital and improved the kidney survival rate more efficiently than IHD did,although only the trend but not statistical significance was observed.
format Article
id doaj-art-80c5db9ac2544e19bcc4fcda33a08a8e
institution Kabale University
issn 1671-2390
language zho
publishDate 2016-01-01
publisher Editorial Department of Journal of Clinical Nephrology
record_format Article
series Linchuang shenzangbing zazhi
spelling doaj-art-80c5db9ac2544e19bcc4fcda33a08a8e2025-08-20T03:52:51ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902016-01-0142342657918335Therapeutic effects of extended daily hemofiltration and intermittent hemodialysis for systemic inflammatory response syndrome with acute kidney injuryFENG Xue-fangZHOU RongXU Ya-hongZHANG YunCHEN Ming-dongSHEN JieObjective To compare the effect of extended daily hemofiltration(EDHF) and intermittent hemodialysis(IHD) for patients with systemic inflammatory response syndrome(SIRS) and acute kidney injury(AKI).Methods Forty patients with SIRS and AKI in Yangpu Hospital from Jan.2010 to May 2013 were collected prospectively.Patients were given EDHF or IHD in addition to the routine management The following endpoints were measured and compared between two groups:the baseline level,the progression of disease(including mortality rate in hospital,kidney survival rate,length and expenses of hospitalization,and the incidence of disease complications),the serum BUN and creatinine levels.Results(1) 17(85%) patients in the EDHF group got through the acute phase of disease and 3(15%) patients did not survive,while in the IHD group 15(75%) patients survived and 5(25%) patients died.No significant difference in survival rate was found between the two groups.Fourteen patients(70%) in the EDHF group got rid of dialysis,while in the IHD group,9out of 20(45%) did There was also no significant difference in kidney survival rate between the two groups.The average days of hospitalization in the EDHF group was(32.6 ± 8.6) days,significantly shorter than in the IHD group(39.2 ± 11.5) days(P<0.05),but the expenses of hospitalization was comparable between two groups(P>0.05).(2) The creatinine level on the 5th day after hemodialysis in the EDHF group was(243.5±92.8) μmol/L,significantly lower than that in the IHD group(363.8 ± 209.0) μmol/L(P<0.05).Conclusions In management of SIRS with AKI,it seemed that the EDHF lowered the mortality rate in hospital and improved the kidney survival rate more efficiently than IHD did,although only the trend but not statistical significance was observed.http://www.lcszb.com/thesisDetails?columnId=57918335&Fpath=home&index=0Extended daily hemofiltrationIntermittent hemodialysisSystemic inflammatory response syndromeAcute kidney injury
spellingShingle FENG Xue-fang
ZHOU Rong
XU Ya-hong
ZHANG Yun
CHEN Ming-dong
SHEN Jie
Therapeutic effects of extended daily hemofiltration and intermittent hemodialysis for systemic inflammatory response syndrome with acute kidney injury
Linchuang shenzangbing zazhi
Extended daily hemofiltration
Intermittent hemodialysis
Systemic inflammatory response syndrome
Acute kidney injury
title Therapeutic effects of extended daily hemofiltration and intermittent hemodialysis for systemic inflammatory response syndrome with acute kidney injury
title_full Therapeutic effects of extended daily hemofiltration and intermittent hemodialysis for systemic inflammatory response syndrome with acute kidney injury
title_fullStr Therapeutic effects of extended daily hemofiltration and intermittent hemodialysis for systemic inflammatory response syndrome with acute kidney injury
title_full_unstemmed Therapeutic effects of extended daily hemofiltration and intermittent hemodialysis for systemic inflammatory response syndrome with acute kidney injury
title_short Therapeutic effects of extended daily hemofiltration and intermittent hemodialysis for systemic inflammatory response syndrome with acute kidney injury
title_sort therapeutic effects of extended daily hemofiltration and intermittent hemodialysis for systemic inflammatory response syndrome with acute kidney injury
topic Extended daily hemofiltration
Intermittent hemodialysis
Systemic inflammatory response syndrome
Acute kidney injury
url http://www.lcszb.com/thesisDetails?columnId=57918335&Fpath=home&index=0
work_keys_str_mv AT fengxuefang therapeuticeffectsofextendeddailyhemofiltrationandintermittenthemodialysisforsystemicinflammatoryresponsesyndromewithacutekidneyinjury
AT zhourong therapeuticeffectsofextendeddailyhemofiltrationandintermittenthemodialysisforsystemicinflammatoryresponsesyndromewithacutekidneyinjury
AT xuyahong therapeuticeffectsofextendeddailyhemofiltrationandintermittenthemodialysisforsystemicinflammatoryresponsesyndromewithacutekidneyinjury
AT zhangyun therapeuticeffectsofextendeddailyhemofiltrationandintermittenthemodialysisforsystemicinflammatoryresponsesyndromewithacutekidneyinjury
AT chenmingdong therapeuticeffectsofextendeddailyhemofiltrationandintermittenthemodialysisforsystemicinflammatoryresponsesyndromewithacutekidneyinjury
AT shenjie therapeuticeffectsofextendeddailyhemofiltrationandintermittenthemodialysisforsystemicinflammatoryresponsesyndromewithacutekidneyinjury