Co-encapsulation of Tamoxifen and Curcumin in PLA Nanoparticles Increases the Antiproliferative Activity over B16-F10 Cells

Co-encapsulation of Tamoxifen and Curcumin in PLA Nanoparticles Increases the Antiproliferative Activity over B16-F10 Cells

Abstract Tamoxifen (TAM) and curcumin (CUR) are compounds investigated for cancer treatment; however, tamoxifen is associated with side effects, especially reducing red blood cells, and curcumin has low bioavailability. Therefore, combining these compounds in an encapsulation system represents a pro...

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Bibliographic Details
Main Authors: Loriangela Marceli Dal Pozzo, Thaysa Ksiaskiewcz Karam, Laís de Almeida Campos, Celso Vataru Nakamura, Rubiana Mara Mainardes, Rafaela Rosa-Ribeiro, Najeh Maissar Khalil
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2025-07-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Nanotechnology
Drug delivery
Hemolysis and Melanoma.
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132025000100307&lng=en&tlng=en
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