Effect of perioperative probiotic intervention on postoperative cognitive dysfunction in elderly patients: a randomized double- blinded and placebo-controlled trial

Effect of perioperative probiotic intervention on postoperative cognitive dysfunction in elderly patients: a randomized double- blinded and placebo-controlled trial

Abstract Background Postoperative cognitive dysfunction (POCD) may last for days, months or even years, leading to prolonged hospitalization and increased costs, increased mortality, and poor quality of life. Although POCD is an important clinical problem, its prevention, treatment strategies and ef...

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Bibliographic Details
Main Authors: Sunan Gao, Hongyu Dai, Qian Hao, Jiale Song, Kang Ji, Hongwei Xu, Gang Chen, Jian Lu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Translational Medicine
Subjects:
Probiotics
Postoperative cognitive dysfunction
Gut microbiota
Gut-brain axis
Online Access:https://doi.org/10.1186/s12967-025-06584-2
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