Treatment Outcomes in Spinal Tumors According to Patients’ Perspectives: A Focus on Indeterminate Spinal Instability
The objective of this study was to analyze treatment approaches and outcomes according to patients’ perspectives for patients with indeterminate spinal instability caused by neoplastic lesions. Data were collected from 31 patients with a total of 147 spinal neoplastic lesions, 29 of whom had lesions...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-01-01
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| Series: | Current Oncology |
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| Online Access: | https://www.mdpi.com/1718-7729/32/1/38 |
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| author | Victoria H. Schimmelpenning Robin Brugger Nikki Rommers Johann Kunst Martin Jäger Christoph E. Albers Helena Milavec |
| author_facet | Victoria H. Schimmelpenning Robin Brugger Nikki Rommers Johann Kunst Martin Jäger Christoph E. Albers Helena Milavec |
| author_sort | Victoria H. Schimmelpenning |
| collection | DOAJ |
| description | The objective of this study was to analyze treatment approaches and outcomes according to patients’ perspectives for patients with indeterminate spinal instability caused by neoplastic lesions. Data were collected from 31 patients with a total of 147 spinal neoplastic lesions, 29 of whom had lesions classified as indeterminate. These lesions were divided into two groups: the low indeterminate group (SINS 7–9) and the high indeterminate group (SINS 10–12). Conservative treatment was the primary approach (93%), resulting in improvement in 59% of cases, stability in 22%, and asymptomatic outcomes in 19%. No significant differences in self-reported outcomes were found between surgical and non-surgical treatments (<i>p</i> = 0.98, <i>p</i> = 0.18). Surgery was reserved for patients with severe pain or impending neurological compromise. Our findings suggest that conservative management is a viable option for most patients with indeterminate spinal instability caused by neoplastic lesions, provided pain and neurological stability are adequately controlled. |
| format | Article |
| id | doaj-art-802d2c63ea0a4200a8240e11f63cb6ce |
| institution | Kabale University |
| issn | 1198-0052 1718-7729 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj-art-802d2c63ea0a4200a8240e11f63cb6ce2025-01-24T13:28:27ZengMDPI AGCurrent Oncology1198-00521718-77292025-01-013213810.3390/curroncol32010038Treatment Outcomes in Spinal Tumors According to Patients’ Perspectives: A Focus on Indeterminate Spinal InstabilityVictoria H. Schimmelpenning0Robin Brugger1Nikki Rommers2Johann Kunst3Martin Jäger4Christoph E. Albers5Helena Milavec6Spine Unit, Department of Orthopaedic Surgery and Traumatology, Aarau Cantonal Hospital, 5001 Aarau, SwitzerlandSpine Unit, Department of Orthopaedic Surgery and Traumatology, Aarau Cantonal Hospital, 5001 Aarau, SwitzerlandDepartment of Clinical Research, University of Basel, University Hospital Basel, 4031 Basel, SwitzerlandSpine Unit, Department of Orthopaedic Surgery and Traumatology, Aarau Cantonal Hospital, 5001 Aarau, SwitzerlandSpine Unit, Department of Orthopaedic Surgery and Traumatology, Aarau Cantonal Hospital, 5001 Aarau, SwitzerlandDepartment of Orthopaedic Surgery and Traumatology, University Hospital Bern, Inselspital, University of Bern, 3010 Bern, SwitzerlandSpine Unit, Department of Orthopaedic Surgery and Traumatology, Aarau Cantonal Hospital, 5001 Aarau, SwitzerlandThe objective of this study was to analyze treatment approaches and outcomes according to patients’ perspectives for patients with indeterminate spinal instability caused by neoplastic lesions. Data were collected from 31 patients with a total of 147 spinal neoplastic lesions, 29 of whom had lesions classified as indeterminate. These lesions were divided into two groups: the low indeterminate group (SINS 7–9) and the high indeterminate group (SINS 10–12). Conservative treatment was the primary approach (93%), resulting in improvement in 59% of cases, stability in 22%, and asymptomatic outcomes in 19%. No significant differences in self-reported outcomes were found between surgical and non-surgical treatments (<i>p</i> = 0.98, <i>p</i> = 0.18). Surgery was reserved for patients with severe pain or impending neurological compromise. Our findings suggest that conservative management is a viable option for most patients with indeterminate spinal instability caused by neoplastic lesions, provided pain and neurological stability are adequately controlled.https://www.mdpi.com/1718-7729/32/1/38spinal neoplastic lesionsindeterminate spinal instabilityspinal instability neoplastic score (SINS)tumortreatment outcomes |
| spellingShingle | Victoria H. Schimmelpenning Robin Brugger Nikki Rommers Johann Kunst Martin Jäger Christoph E. Albers Helena Milavec Treatment Outcomes in Spinal Tumors According to Patients’ Perspectives: A Focus on Indeterminate Spinal Instability Current Oncology spinal neoplastic lesions indeterminate spinal instability spinal instability neoplastic score (SINS) tumor treatment outcomes |
| title | Treatment Outcomes in Spinal Tumors According to Patients’ Perspectives: A Focus on Indeterminate Spinal Instability |
| title_full | Treatment Outcomes in Spinal Tumors According to Patients’ Perspectives: A Focus on Indeterminate Spinal Instability |
| title_fullStr | Treatment Outcomes in Spinal Tumors According to Patients’ Perspectives: A Focus on Indeterminate Spinal Instability |
| title_full_unstemmed | Treatment Outcomes in Spinal Tumors According to Patients’ Perspectives: A Focus on Indeterminate Spinal Instability |
| title_short | Treatment Outcomes in Spinal Tumors According to Patients’ Perspectives: A Focus on Indeterminate Spinal Instability |
| title_sort | treatment outcomes in spinal tumors according to patients perspectives a focus on indeterminate spinal instability |
| topic | spinal neoplastic lesions indeterminate spinal instability spinal instability neoplastic score (SINS) tumor treatment outcomes |
| url | https://www.mdpi.com/1718-7729/32/1/38 |
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