Proximity Labeling-Based Identification of MGAT3 Substrates and Revelation of the Tumor-Suppressive Role of Bisecting GlcNAc in Breast Cancer via GLA Degradation

Glycosylation plays a critical role in various biological processes, yet identifying specific glycosyltransferase substrates remains a challenge due to the complexity of glycosylation. Here, we employ proximity labeling with biotin ligases BASU and TurboID to map the proximitome of MGAT3, a glycosyl...

Full description

Saved in:
Bibliographic Details
Main Authors: Bowen Wang, Xin He, Yue Zhou, Zengqi Tan, Xiang Li, Feng Guan, Lei Lei
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/14/2/103
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items