The Role of Inflammation in the Pathogenesis of Macular Edema Secondary to Retinal Vascular Diseases

Macular edema (ME) is a nonspecific sign of numerous retinal vascular diseases. This paper is an updated overview about the role of inflammatory processes in the genesis of both diabetic macular edema (DME) and ME secondary to retinal vein occlusion (RVO). We focus on the inflammatory mediators im...

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Main Authors: Francisco J. Ascaso, Valentín Huerva, Andrzej Grzybowski
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2014/432685
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author Francisco J. Ascaso
Valentín Huerva
Andrzej Grzybowski
author_facet Francisco J. Ascaso
Valentín Huerva
Andrzej Grzybowski
author_sort Francisco J. Ascaso
collection DOAJ
description Macular edema (ME) is a nonspecific sign of numerous retinal vascular diseases. This paper is an updated overview about the role of inflammatory processes in the genesis of both diabetic macular edema (DME) and ME secondary to retinal vein occlusion (RVO). We focus on the inflammatory mediators implicated, the effect of the different intravitreal therapies, the recruitment of leukocytes mediated by adhesion molecules, and the role of retinal Müller glial (RMG) cells.
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spelling doaj-art-800245bf649044858c8c3d506db4cfd92025-02-03T00:59:28ZengWileyMediators of Inflammation0962-93511466-18612014-01-01201410.1155/2014/432685432685The Role of Inflammation in the Pathogenesis of Macular Edema Secondary to Retinal Vascular DiseasesFrancisco J. Ascaso0Valentín Huerva1Andrzej Grzybowski2Department of Ophthalmology, “Lozano Blesa” University Clinic Hospital, San Juan Bosco 15, 50009 Zaragoza, SpainDepartment of Ophthalmology, University Hospital Arnau de Vilanova, Lleida, SpainDepartment of Ophthalmology, Poznań City Hospital, Poznań, PolandMacular edema (ME) is a nonspecific sign of numerous retinal vascular diseases. This paper is an updated overview about the role of inflammatory processes in the genesis of both diabetic macular edema (DME) and ME secondary to retinal vein occlusion (RVO). We focus on the inflammatory mediators implicated, the effect of the different intravitreal therapies, the recruitment of leukocytes mediated by adhesion molecules, and the role of retinal Müller glial (RMG) cells.http://dx.doi.org/10.1155/2014/432685
spellingShingle Francisco J. Ascaso
Valentín Huerva
Andrzej Grzybowski
The Role of Inflammation in the Pathogenesis of Macular Edema Secondary to Retinal Vascular Diseases
Mediators of Inflammation
title The Role of Inflammation in the Pathogenesis of Macular Edema Secondary to Retinal Vascular Diseases
title_full The Role of Inflammation in the Pathogenesis of Macular Edema Secondary to Retinal Vascular Diseases
title_fullStr The Role of Inflammation in the Pathogenesis of Macular Edema Secondary to Retinal Vascular Diseases
title_full_unstemmed The Role of Inflammation in the Pathogenesis of Macular Edema Secondary to Retinal Vascular Diseases
title_short The Role of Inflammation in the Pathogenesis of Macular Edema Secondary to Retinal Vascular Diseases
title_sort role of inflammation in the pathogenesis of macular edema secondary to retinal vascular diseases
url http://dx.doi.org/10.1155/2014/432685
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