The Role of Inflammation in the Pathogenesis of Macular Edema Secondary to Retinal Vascular Diseases
Macular edema (ME) is a nonspecific sign of numerous retinal vascular diseases. This paper is an updated overview about the role of inflammatory processes in the genesis of both diabetic macular edema (DME) and ME secondary to retinal vein occlusion (RVO). We focus on the inflammatory mediators im...
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Format: | Article |
Language: | English |
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Wiley
2014-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2014/432685 |
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author | Francisco J. Ascaso Valentín Huerva Andrzej Grzybowski |
author_facet | Francisco J. Ascaso Valentín Huerva Andrzej Grzybowski |
author_sort | Francisco J. Ascaso |
collection | DOAJ |
description | Macular edema (ME) is a nonspecific sign of numerous retinal vascular diseases. This paper is an updated overview about the role of inflammatory processes in the genesis of both diabetic macular edema (DME) and ME secondary to retinal vein occlusion (RVO). We focus on the inflammatory mediators implicated, the effect of the different intravitreal therapies, the recruitment of leukocytes mediated by adhesion molecules, and the role of retinal Müller glial (RMG) cells. |
format | Article |
id | doaj-art-800245bf649044858c8c3d506db4cfd9 |
institution | Kabale University |
issn | 0962-9351 1466-1861 |
language | English |
publishDate | 2014-01-01 |
publisher | Wiley |
record_format | Article |
series | Mediators of Inflammation |
spelling | doaj-art-800245bf649044858c8c3d506db4cfd92025-02-03T00:59:28ZengWileyMediators of Inflammation0962-93511466-18612014-01-01201410.1155/2014/432685432685The Role of Inflammation in the Pathogenesis of Macular Edema Secondary to Retinal Vascular DiseasesFrancisco J. Ascaso0Valentín Huerva1Andrzej Grzybowski2Department of Ophthalmology, “Lozano Blesa” University Clinic Hospital, San Juan Bosco 15, 50009 Zaragoza, SpainDepartment of Ophthalmology, University Hospital Arnau de Vilanova, Lleida, SpainDepartment of Ophthalmology, Poznań City Hospital, Poznań, PolandMacular edema (ME) is a nonspecific sign of numerous retinal vascular diseases. This paper is an updated overview about the role of inflammatory processes in the genesis of both diabetic macular edema (DME) and ME secondary to retinal vein occlusion (RVO). We focus on the inflammatory mediators implicated, the effect of the different intravitreal therapies, the recruitment of leukocytes mediated by adhesion molecules, and the role of retinal Müller glial (RMG) cells.http://dx.doi.org/10.1155/2014/432685 |
spellingShingle | Francisco J. Ascaso Valentín Huerva Andrzej Grzybowski The Role of Inflammation in the Pathogenesis of Macular Edema Secondary to Retinal Vascular Diseases Mediators of Inflammation |
title | The Role of Inflammation in the Pathogenesis of Macular Edema Secondary to Retinal Vascular Diseases |
title_full | The Role of Inflammation in the Pathogenesis of Macular Edema Secondary to Retinal Vascular Diseases |
title_fullStr | The Role of Inflammation in the Pathogenesis of Macular Edema Secondary to Retinal Vascular Diseases |
title_full_unstemmed | The Role of Inflammation in the Pathogenesis of Macular Edema Secondary to Retinal Vascular Diseases |
title_short | The Role of Inflammation in the Pathogenesis of Macular Edema Secondary to Retinal Vascular Diseases |
title_sort | role of inflammation in the pathogenesis of macular edema secondary to retinal vascular diseases |
url | http://dx.doi.org/10.1155/2014/432685 |
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