Severe Hyperphosphatemia in a Patient with Mild Acute Kidney Injury

Hyperphosphatemia may arise from various conditions including exogenous ingestion, extracellular shifts due to cell death or alterations in acid-base status, increased bone resorption, hormonal dysregulations leading to reduced renal excretion, reduced kidney function, or faulty measurement techniqu...

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Main Authors: Phuong Chi Pham, Raghu Konanur Ventakaram, Jimmy Pham, Harpreet Sidhu, Nada Bader, Phuong Mai Pham, Phuong Thu Pham
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2021/9962624
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author Phuong Chi Pham
Raghu Konanur Ventakaram
Jimmy Pham
Harpreet Sidhu
Nada Bader
Phuong Mai Pham
Phuong Thu Pham
author_facet Phuong Chi Pham
Raghu Konanur Ventakaram
Jimmy Pham
Harpreet Sidhu
Nada Bader
Phuong Mai Pham
Phuong Thu Pham
author_sort Phuong Chi Pham
collection DOAJ
description Hyperphosphatemia may arise from various conditions including exogenous ingestion, extracellular shifts due to cell death or alterations in acid-base status, increased bone resorption, hormonal dysregulations leading to reduced renal excretion, reduced kidney function, or faulty measurement techniques. We herein present a case of a young pregnant woman who presented with mild acute kidney injury (AKI), invasive mucormycosis receiving liposomal amphotericin, and hyperphosphatemia out of proportion to the degree of kidney injury. While the patient was given routine phosphate-binding agent by her primary care team for presumed AKI-associated hyperphosphatemia, a full investigation by the renal consulting team for contributing factors other than kidney injury revealed that she actually had pseudohyperphosphatemia associated with the use of liposomal amphotericin. Erroneous treatment of pseudohyperphosphatemia may have been detrimental to this pregnant patient. A literature review for conditions associated with pseudohyperphosphatemia other than the use of liposomal amphotericin will be discussed.
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institution Kabale University
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language English
publishDate 2021-01-01
publisher Wiley
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series Case Reports in Medicine
spelling doaj-art-7ff7c16b4dab46d19d7207da8756d22c2025-02-03T06:07:40ZengWileyCase Reports in Medicine1687-96271687-96352021-01-01202110.1155/2021/99626249962624Severe Hyperphosphatemia in a Patient with Mild Acute Kidney InjuryPhuong Chi Pham0Raghu Konanur Ventakaram1Jimmy Pham2Harpreet Sidhu3Nada Bader4Phuong Mai Pham5Phuong Thu Pham6Olive View-UCLA Medical Center, Division of Nephrology, Sylmar, CA, USAOlive View-UCLA Medical Center, Division of Nephrology, Sylmar, CA, USAOlive View-UCLA Medical Center, Division of Nephrology, Sylmar, CA, USAOlive View-UCLA Medical Center, Division of Nephrology, Sylmar, CA, USAOlive View-UCLA Medical Center, Division of Nephrology, Sylmar, CA, USAGreater Los Angeles Veterans Administration, Sepulveda Ambulatory Care Center, Los Angeles, CA, USARonald Reagan UCLA Medical Center, David Geffen School of Medicine, Kidney Transplant Program, Los Angeles, CA, USAHyperphosphatemia may arise from various conditions including exogenous ingestion, extracellular shifts due to cell death or alterations in acid-base status, increased bone resorption, hormonal dysregulations leading to reduced renal excretion, reduced kidney function, or faulty measurement techniques. We herein present a case of a young pregnant woman who presented with mild acute kidney injury (AKI), invasive mucormycosis receiving liposomal amphotericin, and hyperphosphatemia out of proportion to the degree of kidney injury. While the patient was given routine phosphate-binding agent by her primary care team for presumed AKI-associated hyperphosphatemia, a full investigation by the renal consulting team for contributing factors other than kidney injury revealed that she actually had pseudohyperphosphatemia associated with the use of liposomal amphotericin. Erroneous treatment of pseudohyperphosphatemia may have been detrimental to this pregnant patient. A literature review for conditions associated with pseudohyperphosphatemia other than the use of liposomal amphotericin will be discussed.http://dx.doi.org/10.1155/2021/9962624
spellingShingle Phuong Chi Pham
Raghu Konanur Ventakaram
Jimmy Pham
Harpreet Sidhu
Nada Bader
Phuong Mai Pham
Phuong Thu Pham
Severe Hyperphosphatemia in a Patient with Mild Acute Kidney Injury
Case Reports in Medicine
title Severe Hyperphosphatemia in a Patient with Mild Acute Kidney Injury
title_full Severe Hyperphosphatemia in a Patient with Mild Acute Kidney Injury
title_fullStr Severe Hyperphosphatemia in a Patient with Mild Acute Kidney Injury
title_full_unstemmed Severe Hyperphosphatemia in a Patient with Mild Acute Kidney Injury
title_short Severe Hyperphosphatemia in a Patient with Mild Acute Kidney Injury
title_sort severe hyperphosphatemia in a patient with mild acute kidney injury
url http://dx.doi.org/10.1155/2021/9962624
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