Symptomatic Secondary Selective IgM Immunodeficiency in Adult Man with Undiagnosed Celiac Disease
Selective IgM immunodeficiency (SIgMID) is a heterogeneous disorder with no known genetic background and may occur as a primary or a secondary condition. Celiac disease has been reported in association with several humeral immunodeficiencies, including isolated severe selective IgA deficiency, panhy...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Immunology |
| Online Access: | http://dx.doi.org/10.1155/2012/684247 |
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| _version_ | 1832561923498967040 |
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| author | Eli Magen Viktor Feldman Mishal Joseph Hadari Israel |
| author_facet | Eli Magen Viktor Feldman Mishal Joseph Hadari Israel |
| author_sort | Eli Magen |
| collection | DOAJ |
| description | Selective IgM immunodeficiency (SIgMID) is a heterogeneous disorder with no known genetic background and may occur as a primary or a secondary condition. Celiac disease has been reported in association with several humeral immunodeficiencies, including isolated severe selective IgA deficiency, panhypogammaglobulinemia, and isolated combined IgA and IgM deficiency. There are only few reported cases of pediatric and adult patients with SIgMID and celiac disease. In this paper, we describe an adult patient with a symptomatic secondary SIgMID associated with undiagnosed celiac disease, with a resolution of clinical symptoms of immunodeficiency and serum IgM normalization following a gluten-free diet. |
| format | Article |
| id | doaj-art-7fa42b32195247c4aaebf94cdcd6a2bc |
| institution | Kabale University |
| issn | 2090-6609 2090-6617 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Immunology |
| spelling | doaj-art-7fa42b32195247c4aaebf94cdcd6a2bc2025-02-03T01:23:55ZengWileyCase Reports in Immunology2090-66092090-66172012-01-01201210.1155/2012/684247684247Symptomatic Secondary Selective IgM Immunodeficiency in Adult Man with Undiagnosed Celiac DiseaseEli Magen0Viktor Feldman1Mishal Joseph2Hadari Israel3Leumit Health Services, Ashkelon, IsraelOrthopedic Department, Meir Medical Center, Kfar Saba, IsraelMedicine B Department, Barzilai Medical Center, 78306 Ashkelon, IsraelLeumit Health Services, Ashkelon, IsraelSelective IgM immunodeficiency (SIgMID) is a heterogeneous disorder with no known genetic background and may occur as a primary or a secondary condition. Celiac disease has been reported in association with several humeral immunodeficiencies, including isolated severe selective IgA deficiency, panhypogammaglobulinemia, and isolated combined IgA and IgM deficiency. There are only few reported cases of pediatric and adult patients with SIgMID and celiac disease. In this paper, we describe an adult patient with a symptomatic secondary SIgMID associated with undiagnosed celiac disease, with a resolution of clinical symptoms of immunodeficiency and serum IgM normalization following a gluten-free diet.http://dx.doi.org/10.1155/2012/684247 |
| spellingShingle | Eli Magen Viktor Feldman Mishal Joseph Hadari Israel Symptomatic Secondary Selective IgM Immunodeficiency in Adult Man with Undiagnosed Celiac Disease Case Reports in Immunology |
| title | Symptomatic Secondary Selective IgM Immunodeficiency in Adult Man with Undiagnosed Celiac Disease |
| title_full | Symptomatic Secondary Selective IgM Immunodeficiency in Adult Man with Undiagnosed Celiac Disease |
| title_fullStr | Symptomatic Secondary Selective IgM Immunodeficiency in Adult Man with Undiagnosed Celiac Disease |
| title_full_unstemmed | Symptomatic Secondary Selective IgM Immunodeficiency in Adult Man with Undiagnosed Celiac Disease |
| title_short | Symptomatic Secondary Selective IgM Immunodeficiency in Adult Man with Undiagnosed Celiac Disease |
| title_sort | symptomatic secondary selective igm immunodeficiency in adult man with undiagnosed celiac disease |
| url | http://dx.doi.org/10.1155/2012/684247 |
| work_keys_str_mv | AT elimagen symptomaticsecondaryselectiveigmimmunodeficiencyinadultmanwithundiagnosedceliacdisease AT viktorfeldman symptomaticsecondaryselectiveigmimmunodeficiencyinadultmanwithundiagnosedceliacdisease AT mishaljoseph symptomaticsecondaryselectiveigmimmunodeficiencyinadultmanwithundiagnosedceliacdisease AT hadariisrael symptomaticsecondaryselectiveigmimmunodeficiencyinadultmanwithundiagnosedceliacdisease |