TB SKIN TEST RESPONSE IN CHILDREN WITH HIV INFECTION

The paper presents the results of tuberculin and recombinant tuberculosis allergen (diaskintest) skin tests in HIV-infected children with tuberculosis. In general, the conducted investigations have shown that the tuberculin tests are of definite value in diagnosing tuberculosis in HIV-infected child...

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Main Author: N. I. Klevno
Format: Article
Language:Russian
Published: New Terra Publishing House 2014-07-01
Series:Туберкулез и болезни лёгких
Subjects:
Online Access:https://www.tibl-journal.com/jour/article/view/102
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author N. I. Klevno
author_facet N. I. Klevno
author_sort N. I. Klevno
collection DOAJ
description The paper presents the results of tuberculin and recombinant tuberculosis allergen (diaskintest) skin tests in HIV-infected children with tuberculosis. In general, the conducted investigations have shown that the tuberculin tests are of definite value in diagnosing tuberculosis in HIV-infected children. However, the lower the blood CD4 lymphocyte count, the less frequently the positive skin tests were recorded: the rate of recorded positive tuberculin tests was nearly 20% in patients with CD4 counts less than 200 cells/µl and it approximated those (within 85%) in non-HIV-infected patients with CD4 counts more than 500 cells/µl. The susceptibility to the diaskintest also decreased as immunodeficiency increased and it was comparable to that of the tuberculin test.
format Article
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institution OA Journals
issn 2075-1230
2542-1506
language Russian
publishDate 2014-07-01
publisher New Terra Publishing House
record_format Article
series Туберкулез и болезни лёгких
spelling doaj-art-7fa31faf7e5e4e5697cbf77be1aaea1b2025-08-20T01:47:34ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062014-07-01073740102TB SKIN TEST RESPONSE IN CHILDREN WITH HIV INFECTIONN. I. Klevno0НИИ фтизиопульмонологии ГБОУ ВПО «Первый МГМУ им. И. М. Сеченова»The paper presents the results of tuberculin and recombinant tuberculosis allergen (diaskintest) skin tests in HIV-infected children with tuberculosis. In general, the conducted investigations have shown that the tuberculin tests are of definite value in diagnosing tuberculosis in HIV-infected children. However, the lower the blood CD4 lymphocyte count, the less frequently the positive skin tests were recorded: the rate of recorded positive tuberculin tests was nearly 20% in patients with CD4 counts less than 200 cells/µl and it approximated those (within 85%) in non-HIV-infected patients with CD4 counts more than 500 cells/µl. The susceptibility to the diaskintest also decreased as immunodeficiency increased and it was comparable to that of the tuberculin test.https://www.tibl-journal.com/jour/article/view/102childrentuberculosishiv infectionmantoux testdiaskintest
spellingShingle N. I. Klevno
TB SKIN TEST RESPONSE IN CHILDREN WITH HIV INFECTION
Туберкулез и болезни лёгких
children
tuberculosis
hiv infection
mantoux test
diaskintest
title TB SKIN TEST RESPONSE IN CHILDREN WITH HIV INFECTION
title_full TB SKIN TEST RESPONSE IN CHILDREN WITH HIV INFECTION
title_fullStr TB SKIN TEST RESPONSE IN CHILDREN WITH HIV INFECTION
title_full_unstemmed TB SKIN TEST RESPONSE IN CHILDREN WITH HIV INFECTION
title_short TB SKIN TEST RESPONSE IN CHILDREN WITH HIV INFECTION
title_sort tb skin test response in children with hiv infection
topic children
tuberculosis
hiv infection
mantoux test
diaskintest
url https://www.tibl-journal.com/jour/article/view/102
work_keys_str_mv AT niklevno tbskintestresponseinchildrenwithhivinfection