Acute Oxalate Nephropathy Associated with Orlistat: A Case Report with a Review of the Literature
Orlistat is a gastrointestinal lipase inhibitor used for weight reduction in obese individuals. Enteric hyperoxaluria caused by orlistat leads to oxalate absorption. Acute oxalate nephropathy is a rare complication of treatment with orlistat. Herein we report a patient presenting with acute renal fa...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2013/124604 |
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| _version_ | 1832552862610096128 |
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| author | Dhara Chaudhari Conchitina Crisostomo Charles Ganote George Youngberg |
| author_facet | Dhara Chaudhari Conchitina Crisostomo Charles Ganote George Youngberg |
| author_sort | Dhara Chaudhari |
| collection | DOAJ |
| description | Orlistat is a gastrointestinal lipase inhibitor used for weight reduction in obese individuals. Enteric hyperoxaluria caused by orlistat leads to oxalate absorption. Acute oxalate nephropathy is a rare complication of treatment with orlistat. Herein we report a patient presenting with acute renal failure which improved minimal with intravenous hydration. She was found to have oxalate crystals on renal biopsy. Patient admitted orlistat use over the counter for weight reduction on further questioning. The purpose of this case review is to increase awareness among patients since they are more focused on losing weight. This case also calls for the provider attention to educate patients regarding side effects of orlistat because of easy availability of orlistat over the counter. |
| format | Article |
| id | doaj-art-7f913af2451d404e82a90b20f1c248e9 |
| institution | Kabale University |
| issn | 2090-6641 2090-665X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-7f913af2451d404e82a90b20f1c248e92025-02-03T05:57:36ZengWileyCase Reports in Nephrology2090-66412090-665X2013-01-01201310.1155/2013/124604124604Acute Oxalate Nephropathy Associated with Orlistat: A Case Report with a Review of the LiteratureDhara Chaudhari0Conchitina Crisostomo1Charles Ganote2George Youngberg3Department of Internal Medicine, East Tennessee State University, Quillen College of Medicine, Johnson City, TN 37615, USADepartment of Nephrology, East Tennessee State University, Quillen College of Medicine, Johnson City, TN 37615, USADepartment of Pathology, East Tennessee State University, Quillen College of Medicine, Johnson City, TN 37615, USADepartment of Pathology, East Tennessee State University, Quillen College of Medicine, Johnson City, TN 37615, USAOrlistat is a gastrointestinal lipase inhibitor used for weight reduction in obese individuals. Enteric hyperoxaluria caused by orlistat leads to oxalate absorption. Acute oxalate nephropathy is a rare complication of treatment with orlistat. Herein we report a patient presenting with acute renal failure which improved minimal with intravenous hydration. She was found to have oxalate crystals on renal biopsy. Patient admitted orlistat use over the counter for weight reduction on further questioning. The purpose of this case review is to increase awareness among patients since they are more focused on losing weight. This case also calls for the provider attention to educate patients regarding side effects of orlistat because of easy availability of orlistat over the counter.http://dx.doi.org/10.1155/2013/124604 |
| spellingShingle | Dhara Chaudhari Conchitina Crisostomo Charles Ganote George Youngberg Acute Oxalate Nephropathy Associated with Orlistat: A Case Report with a Review of the Literature Case Reports in Nephrology |
| title | Acute Oxalate Nephropathy Associated with Orlistat: A Case Report with a Review of the Literature |
| title_full | Acute Oxalate Nephropathy Associated with Orlistat: A Case Report with a Review of the Literature |
| title_fullStr | Acute Oxalate Nephropathy Associated with Orlistat: A Case Report with a Review of the Literature |
| title_full_unstemmed | Acute Oxalate Nephropathy Associated with Orlistat: A Case Report with a Review of the Literature |
| title_short | Acute Oxalate Nephropathy Associated with Orlistat: A Case Report with a Review of the Literature |
| title_sort | acute oxalate nephropathy associated with orlistat a case report with a review of the literature |
| url | http://dx.doi.org/10.1155/2013/124604 |
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