Behçet’s disease: recurrent ischemic stroke as an initial presentation – a case based review

Behçet’s disease (BD) is a rare systemic vasculitis that is characterized by recurrent oral and genital ulcers, uveitis, and skin lesions. Although neurological involvement is a known complication, ischemic stroke remains uncommon. Herein, we report a 37-year-old Kuwaiti woman who experienced recurr...

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Main Authors: Anwar Albasri, Wesam Gouda, Faisal Alsaqabi, Mahmoud M. Magdy, Ashraf A. Mostafa, Nehal El Ghobashy
Format: Article
Language:English
Published: SAGE Publishing 2025-01-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605241311446
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author Anwar Albasri
Wesam Gouda
Faisal Alsaqabi
Mahmoud M. Magdy
Ashraf A. Mostafa
Nehal El Ghobashy
author_facet Anwar Albasri
Wesam Gouda
Faisal Alsaqabi
Mahmoud M. Magdy
Ashraf A. Mostafa
Nehal El Ghobashy
author_sort Anwar Albasri
collection DOAJ
description Behçet’s disease (BD) is a rare systemic vasculitis that is characterized by recurrent oral and genital ulcers, uveitis, and skin lesions. Although neurological involvement is a known complication, ischemic stroke remains uncommon. Herein, we report a 37-year-old Kuwaiti woman who experienced recurrent ischemic stroke with no traditional risk factors. Imaging studies, including magnetic resonance imaging and angiography, confirmed the diagnosis of recurrent ischemic stroke and identified the underlying vasculitic changes. A detailed examination revealed a history of recurrent orogenital ulcers, leading to a diagnosis of BD. High-dose corticosteroids, azathioprine, and antiplatelet treatment were effectively used to manage her acute strokes and underlying vasculitis, thus preventing further thrombotic events. Our case report underscores the difficulties of diagnosing BD with ischemic stroke as the initial manifestation and emphasizes the importance of a multidisciplinary approach that involves rheumatologists, neurologists, and radiologists to create an effective treatment plan. Our findings also underscore the need for medical practitioners to be more knowledgeable about ischemic stroke in young patients without risk factors from endemic areas of BD, and to develop effective therapy plans. Our review of the English literature indicates that this is only the fifth report of stroke as the first presentation of BD.
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institution Kabale University
issn 1473-2300
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publisher SAGE Publishing
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series Journal of International Medical Research
spelling doaj-art-7f852c847f754dba808cdc38d94bcaed2025-01-29T12:03:54ZengSAGE PublishingJournal of International Medical Research1473-23002025-01-015310.1177/03000605241311446Behçet’s disease: recurrent ischemic stroke as an initial presentation – a case based reviewAnwar AlbasriWesam GoudaFaisal AlsaqabiMahmoud M. MagdyAshraf A. MostafaNehal El GhobashyBehçet’s disease (BD) is a rare systemic vasculitis that is characterized by recurrent oral and genital ulcers, uveitis, and skin lesions. Although neurological involvement is a known complication, ischemic stroke remains uncommon. Herein, we report a 37-year-old Kuwaiti woman who experienced recurrent ischemic stroke with no traditional risk factors. Imaging studies, including magnetic resonance imaging and angiography, confirmed the diagnosis of recurrent ischemic stroke and identified the underlying vasculitic changes. A detailed examination revealed a history of recurrent orogenital ulcers, leading to a diagnosis of BD. High-dose corticosteroids, azathioprine, and antiplatelet treatment were effectively used to manage her acute strokes and underlying vasculitis, thus preventing further thrombotic events. Our case report underscores the difficulties of diagnosing BD with ischemic stroke as the initial manifestation and emphasizes the importance of a multidisciplinary approach that involves rheumatologists, neurologists, and radiologists to create an effective treatment plan. Our findings also underscore the need for medical practitioners to be more knowledgeable about ischemic stroke in young patients without risk factors from endemic areas of BD, and to develop effective therapy plans. Our review of the English literature indicates that this is only the fifth report of stroke as the first presentation of BD.https://doi.org/10.1177/03000605241311446
spellingShingle Anwar Albasri
Wesam Gouda
Faisal Alsaqabi
Mahmoud M. Magdy
Ashraf A. Mostafa
Nehal El Ghobashy
Behçet’s disease: recurrent ischemic stroke as an initial presentation – a case based review
Journal of International Medical Research
title Behçet’s disease: recurrent ischemic stroke as an initial presentation – a case based review
title_full Behçet’s disease: recurrent ischemic stroke as an initial presentation – a case based review
title_fullStr Behçet’s disease: recurrent ischemic stroke as an initial presentation – a case based review
title_full_unstemmed Behçet’s disease: recurrent ischemic stroke as an initial presentation – a case based review
title_short Behçet’s disease: recurrent ischemic stroke as an initial presentation – a case based review
title_sort behcet s disease recurrent ischemic stroke as an initial presentation a case based review
url https://doi.org/10.1177/03000605241311446
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