The Role of Insulin-like Growth Factor-Binding Protein-3 in Cancer and Inflammation: From Molecular Mechanisms to Clinical Applications

The Role of Insulin-like Growth Factor-Binding Protein-3 in Cancer and Inflammation: From Molecular Mechanisms to Clinical Applications

Insulin-like growth factor binding protein-3 (IGFBP-3), a member of the IGFBP family, plays an extensive role in cellular growth regulation. By specifically binding to insulin-like growth factors (IGFs), this protein modulates their accessibility to specific receptors, thereby inhibiting IGFs and su...

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Bibliographic Details
Main Authors: hourolein arab, Mohammad Shokrzadeh, Mahboubeh Rahmati, Mohammad Reza Mofid
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences 2025-05-01
Series:Journal of Mazandaran University of Medical Sciences
Subjects:
apoptosis
cancer
igfbp-3
inflammation
tumor growth
Online Access:http://jmums.mazums.ac.ir/article-1-21863-en.pdf
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