Joint Brain Parametric T1-Map Segmentation and RF Inhomogeneity Calibration

We propose a constrained version of Mumford and Shah's (1989) segmentation model with an information-theoretic point of view in order to devise a systematic procedure to segment brain magnetic resonance imaging (MRI) data for parametric T1-Map and T1-weighted images, in both 2-D and 3D settings...

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Main Authors: Ping-Feng Chen, R. Grant Steen, Anthony Yezzi, Hamid Krim
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/2009/269525
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author Ping-Feng Chen
R. Grant Steen
Anthony Yezzi
Hamid Krim
author_facet Ping-Feng Chen
R. Grant Steen
Anthony Yezzi
Hamid Krim
author_sort Ping-Feng Chen
collection DOAJ
description We propose a constrained version of Mumford and Shah's (1989) segmentation model with an information-theoretic point of view in order to devise a systematic procedure to segment brain magnetic resonance imaging (MRI) data for parametric T1-Map and T1-weighted images, in both 2-D and 3D settings. Incorporation of a tuning weight in particular adds a probabilistic flavor to our segmentation method, and makes the 3-tissue segmentation possible. Moreover, we proposed a novel method to jointly segment the T1-Map and calibrate RF Inhomogeneity (JSRIC). This method assumes the average T1 value of white matter is the same across transverse slices in the central brain region, and JSRIC is able to rectify the flip angles to generate calibrated T1-Maps. In order to generate an accurate T1-Map, the determination of optimal flip-angles and the registration of flip-angle images are examined. Our JSRIC method is validated on two human subjects in the 2D T1-Map modality and our segmentation method is validated by two public databases, BrainWeb and IBSR, of T1-weighted modality in the 3D setting.
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institution Kabale University
issn 1687-4188
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series International Journal of Biomedical Imaging
spelling doaj-art-7f50931d814d434295891fbd7a553dd02025-02-03T06:11:54ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962009-01-01200910.1155/2009/269525269525Joint Brain Parametric T1-Map Segmentation and RF Inhomogeneity CalibrationPing-Feng Chen0R. Grant Steen1Anthony Yezzi2Hamid Krim3Department of Electrical and Computer Engineering, North Carolina State University, NC 27695, USAMedical Communications Consultants, LLC 103 Van Doren Place Chapel Hill, NC 27517, USASchool of Electrical and Computer Engineering, Georgia Institute of Technology, GA 30332, USADepartment of Electrical and Computer Engineering, North Carolina State University, NC 27695, USAWe propose a constrained version of Mumford and Shah's (1989) segmentation model with an information-theoretic point of view in order to devise a systematic procedure to segment brain magnetic resonance imaging (MRI) data for parametric T1-Map and T1-weighted images, in both 2-D and 3D settings. Incorporation of a tuning weight in particular adds a probabilistic flavor to our segmentation method, and makes the 3-tissue segmentation possible. Moreover, we proposed a novel method to jointly segment the T1-Map and calibrate RF Inhomogeneity (JSRIC). This method assumes the average T1 value of white matter is the same across transverse slices in the central brain region, and JSRIC is able to rectify the flip angles to generate calibrated T1-Maps. In order to generate an accurate T1-Map, the determination of optimal flip-angles and the registration of flip-angle images are examined. Our JSRIC method is validated on two human subjects in the 2D T1-Map modality and our segmentation method is validated by two public databases, BrainWeb and IBSR, of T1-weighted modality in the 3D setting.http://dx.doi.org/10.1155/2009/269525
spellingShingle Ping-Feng Chen
R. Grant Steen
Anthony Yezzi
Hamid Krim
Joint Brain Parametric T1-Map Segmentation and RF Inhomogeneity Calibration
International Journal of Biomedical Imaging
title Joint Brain Parametric T1-Map Segmentation and RF Inhomogeneity Calibration
title_full Joint Brain Parametric T1-Map Segmentation and RF Inhomogeneity Calibration
title_fullStr Joint Brain Parametric T1-Map Segmentation and RF Inhomogeneity Calibration
title_full_unstemmed Joint Brain Parametric T1-Map Segmentation and RF Inhomogeneity Calibration
title_short Joint Brain Parametric T1-Map Segmentation and RF Inhomogeneity Calibration
title_sort joint brain parametric t1 map segmentation and rf inhomogeneity calibration
url http://dx.doi.org/10.1155/2009/269525
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AT anthonyyezzi jointbrainparametrict1mapsegmentationandrfinhomogeneitycalibration
AT hamidkrim jointbrainparametrict1mapsegmentationandrfinhomogeneitycalibration