Primary Cutaneous Diffuse Large B-Cell Lymphoma of the Upper Limb: Double Hit/Double Expressor with CNS Involvement: From Hospice to Remission
We report a patient with diffuse large B-cell lymphoma of skin, nongerminal center type double hit double expressor, with an initial presentation as a left forearm mass. The patient underwent chemotherapy after initial diagnosis. After chemotherapy regimen, she developed a second mass, followed by C...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2019/3953470 |
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| _version_ | 1832561097378365440 |
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| author | Brenda S. Castillo Maria L. Rodriguez Ju-Hsien John Chao Behyar Zoghi |
| author_facet | Brenda S. Castillo Maria L. Rodriguez Ju-Hsien John Chao Behyar Zoghi |
| author_sort | Brenda S. Castillo |
| collection | DOAJ |
| description | We report a patient with diffuse large B-cell lymphoma of skin, nongerminal center type double hit double expressor, with an initial presentation as a left forearm mass. The patient underwent chemotherapy after initial diagnosis. After chemotherapy regimen, she developed a second mass, followed by CNS involvement with neurological defects. At this time, a three line of chemotherapy was used with minimal effects. The patient was deemed terminal and was recommended hospice care. The patient decided to continue with skin and crainospinal radiotherapy and intrathecal chemotherapy; she achieved complete remission. After achieving complete remission, the patient underwent an autologous stem cell transplant with minimal transplant-related toxicity. |
| format | Article |
| id | doaj-art-7f2f6ed82ce143baaa7de12420f74a33 |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-7f2f6ed82ce143baaa7de12420f74a332025-02-03T01:26:00ZengWileyCase Reports in Hematology2090-65602090-65792019-01-01201910.1155/2019/39534703953470Primary Cutaneous Diffuse Large B-Cell Lymphoma of the Upper Limb: Double Hit/Double Expressor with CNS Involvement: From Hospice to RemissionBrenda S. Castillo0Maria L. Rodriguez1Ju-Hsien John Chao2Behyar Zoghi3Texas Tech University Health Sciences Center Paul L. Foster School of Medicine, El Paso, Texas, USABrown University, Providence, RI, USAMethodist Hospital, Texas Transplant Institute, San Antonio, Texas, USAMethodist Hospital, Texas Transplant Institute, San Antonio, Texas, USAWe report a patient with diffuse large B-cell lymphoma of skin, nongerminal center type double hit double expressor, with an initial presentation as a left forearm mass. The patient underwent chemotherapy after initial diagnosis. After chemotherapy regimen, she developed a second mass, followed by CNS involvement with neurological defects. At this time, a three line of chemotherapy was used with minimal effects. The patient was deemed terminal and was recommended hospice care. The patient decided to continue with skin and crainospinal radiotherapy and intrathecal chemotherapy; she achieved complete remission. After achieving complete remission, the patient underwent an autologous stem cell transplant with minimal transplant-related toxicity.http://dx.doi.org/10.1155/2019/3953470 |
| spellingShingle | Brenda S. Castillo Maria L. Rodriguez Ju-Hsien John Chao Behyar Zoghi Primary Cutaneous Diffuse Large B-Cell Lymphoma of the Upper Limb: Double Hit/Double Expressor with CNS Involvement: From Hospice to Remission Case Reports in Hematology |
| title | Primary Cutaneous Diffuse Large B-Cell Lymphoma of the Upper Limb: Double Hit/Double Expressor with CNS Involvement: From Hospice to Remission |
| title_full | Primary Cutaneous Diffuse Large B-Cell Lymphoma of the Upper Limb: Double Hit/Double Expressor with CNS Involvement: From Hospice to Remission |
| title_fullStr | Primary Cutaneous Diffuse Large B-Cell Lymphoma of the Upper Limb: Double Hit/Double Expressor with CNS Involvement: From Hospice to Remission |
| title_full_unstemmed | Primary Cutaneous Diffuse Large B-Cell Lymphoma of the Upper Limb: Double Hit/Double Expressor with CNS Involvement: From Hospice to Remission |
| title_short | Primary Cutaneous Diffuse Large B-Cell Lymphoma of the Upper Limb: Double Hit/Double Expressor with CNS Involvement: From Hospice to Remission |
| title_sort | primary cutaneous diffuse large b cell lymphoma of the upper limb double hit double expressor with cns involvement from hospice to remission |
| url | http://dx.doi.org/10.1155/2019/3953470 |
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