Global trends and age-specific incidence and mortality of cervical cancer from 1990 to 2019: an international comparative study based on the Global Burden of Disease
Objective To describe the trends of incidence and mortality of cervical cancer in different age groups and regions from 1990 to 2019.Design An international comparative study based on the Global Burden of Disease (GBD) study estimates.Participants Data were publicly available and individuals were no...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2022-07-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/7/e055470.full |
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| author | Juan Du Han Xiao Meng Yang Hong Mei Hui Lu Feiyan Xiang |
| author_facet | Juan Du Han Xiao Meng Yang Hong Mei Hui Lu Feiyan Xiang |
| author_sort | Juan Du |
| collection | DOAJ |
| description | Objective To describe the trends of incidence and mortality of cervical cancer in different age groups and regions from 1990 to 2019.Design An international comparative study based on the Global Burden of Disease (GBD) study estimates.Participants Data were publicly available and individuals were not involved.Methods We collected detailed information on cervical cancer from the GBD study between 1990 and 2019. Average annual percentage changes (AAPCs) of age-standardised incidence and mortality rate (ASIR and ASMR) in cervical cancer, by age group and region, were calculated to quantify the temporal trends.Results Globally, the absolute numbers of incident cases and deaths were increasing, with the most cervical cancer cases and deaths being reported in China, India and Brazil. Although the ASIR and ASMR have declined overall from 1990 to 2019, an increasing or stable trend was also observed in East Asia and Southern sub-Saharan Africa. Particularly, we found that the age-specific AAPC of incidence showed an increasing trend in the age group of 15–49 years globally, and the high Sociodemographic Index region increased the most.Conclusions Cervical cancer remains a concerning disease that affects women all over the world, although the ASIR and ASMR are decreasing. Efforts to control the younger trend and to reduce the disparity between regions are imminent. |
| format | Article |
| id | doaj-art-7f29f2b4f9f54fee92fca77e186b8e3a |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-07-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-7f29f2b4f9f54fee92fca77e186b8e3a2025-01-30T20:25:15ZengBMJ Publishing GroupBMJ Open2044-60552022-07-0112710.1136/bmjopen-2021-055470Global trends and age-specific incidence and mortality of cervical cancer from 1990 to 2019: an international comparative study based on the Global Burden of DiseaseJuan DuHan Xiao0Meng Yang1Hong Mei2Hui Lu3Feiyan Xiang4Department of Economics, University of California Santa Barbara, Santa Barbara, California, USAWuhan Children’s Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Institute of Maternal and Child Health, Wuhan, Hubei, ChinaWuhan Children’s Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Institute of Maternal and Child Health, Wuhan, Hubei, ChinaWuhan Children’s Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Institute of Maternal and Child Health, Wuhan, Hubei, ChinaWuhan Children’s Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Institute of Maternal and Child Health, Wuhan, Hubei, ChinaObjective To describe the trends of incidence and mortality of cervical cancer in different age groups and regions from 1990 to 2019.Design An international comparative study based on the Global Burden of Disease (GBD) study estimates.Participants Data were publicly available and individuals were not involved.Methods We collected detailed information on cervical cancer from the GBD study between 1990 and 2019. Average annual percentage changes (AAPCs) of age-standardised incidence and mortality rate (ASIR and ASMR) in cervical cancer, by age group and region, were calculated to quantify the temporal trends.Results Globally, the absolute numbers of incident cases and deaths were increasing, with the most cervical cancer cases and deaths being reported in China, India and Brazil. Although the ASIR and ASMR have declined overall from 1990 to 2019, an increasing or stable trend was also observed in East Asia and Southern sub-Saharan Africa. Particularly, we found that the age-specific AAPC of incidence showed an increasing trend in the age group of 15–49 years globally, and the high Sociodemographic Index region increased the most.Conclusions Cervical cancer remains a concerning disease that affects women all over the world, although the ASIR and ASMR are decreasing. Efforts to control the younger trend and to reduce the disparity between regions are imminent.https://bmjopen.bmj.com/content/12/7/e055470.full |
| spellingShingle | Juan Du Han Xiao Meng Yang Hong Mei Hui Lu Feiyan Xiang Global trends and age-specific incidence and mortality of cervical cancer from 1990 to 2019: an international comparative study based on the Global Burden of Disease BMJ Open |
| title | Global trends and age-specific incidence and mortality of cervical cancer from 1990 to 2019: an international comparative study based on the Global Burden of Disease |
| title_full | Global trends and age-specific incidence and mortality of cervical cancer from 1990 to 2019: an international comparative study based on the Global Burden of Disease |
| title_fullStr | Global trends and age-specific incidence and mortality of cervical cancer from 1990 to 2019: an international comparative study based on the Global Burden of Disease |
| title_full_unstemmed | Global trends and age-specific incidence and mortality of cervical cancer from 1990 to 2019: an international comparative study based on the Global Burden of Disease |
| title_short | Global trends and age-specific incidence and mortality of cervical cancer from 1990 to 2019: an international comparative study based on the Global Burden of Disease |
| title_sort | global trends and age specific incidence and mortality of cervical cancer from 1990 to 2019 an international comparative study based on the global burden of disease |
| url | https://bmjopen.bmj.com/content/12/7/e055470.full |
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