When a Seemingly Harmless Prescription Turns into Toxicity

Valacyclovir neurotoxicity is commonly seen in the elderly and those with impaired renal function. Differential diagnosis can be challenging as a myriad of medical conditions, including herpes zoster virus associated encephalitis, may present in a similar fashion. We present a case of a 71-year-old...

Full description

Saved in:
Bibliographic Details
Main Authors: Zurab Azmaiparashvili, Kevin Bryan Lo, Nawal Habib, Annie Hsieh
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2018/9724390
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832550083800858624
author Zurab Azmaiparashvili
Kevin Bryan Lo
Nawal Habib
Annie Hsieh
author_facet Zurab Azmaiparashvili
Kevin Bryan Lo
Nawal Habib
Annie Hsieh
author_sort Zurab Azmaiparashvili
collection DOAJ
description Valacyclovir neurotoxicity is commonly seen in the elderly and those with impaired renal function. Differential diagnosis can be challenging as a myriad of medical conditions, including herpes zoster virus associated encephalitis, may present in a similar fashion. We present a case of a 71-year-old male who presented with altered mental status in the setting of recent herpes zoster eruption. His condition was attributed to valacyclovir neurotoxicity, and initiation of appropriate supportive therapy was met with complete resolution of symptoms and normalization of cognitive function.
format Article
id doaj-art-7f29c4cf38fb4bbf88da1d85c2992cb5
institution Kabale University
issn 1687-9627
1687-9635
language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Case Reports in Medicine
spelling doaj-art-7f29c4cf38fb4bbf88da1d85c2992cb52025-02-03T06:07:50ZengWileyCase Reports in Medicine1687-96271687-96352018-01-01201810.1155/2018/97243909724390When a Seemingly Harmless Prescription Turns into ToxicityZurab Azmaiparashvili0Kevin Bryan Lo1Nawal Habib2Annie Hsieh3Department of Medicine, Albert Einstein Medical Center, Philadelphia, PA, USADepartment of Medicine, Albert Einstein Medical Center, Philadelphia, PA, USADepartment of Medicine, Albert Einstein Medical Center, Philadelphia, PA, USADepartment of Neurology, Albert Einstein Medical Center, Philadelphia, PA, USAValacyclovir neurotoxicity is commonly seen in the elderly and those with impaired renal function. Differential diagnosis can be challenging as a myriad of medical conditions, including herpes zoster virus associated encephalitis, may present in a similar fashion. We present a case of a 71-year-old male who presented with altered mental status in the setting of recent herpes zoster eruption. His condition was attributed to valacyclovir neurotoxicity, and initiation of appropriate supportive therapy was met with complete resolution of symptoms and normalization of cognitive function.http://dx.doi.org/10.1155/2018/9724390
spellingShingle Zurab Azmaiparashvili
Kevin Bryan Lo
Nawal Habib
Annie Hsieh
When a Seemingly Harmless Prescription Turns into Toxicity
Case Reports in Medicine
title When a Seemingly Harmless Prescription Turns into Toxicity
title_full When a Seemingly Harmless Prescription Turns into Toxicity
title_fullStr When a Seemingly Harmless Prescription Turns into Toxicity
title_full_unstemmed When a Seemingly Harmless Prescription Turns into Toxicity
title_short When a Seemingly Harmless Prescription Turns into Toxicity
title_sort when a seemingly harmless prescription turns into toxicity
url http://dx.doi.org/10.1155/2018/9724390
work_keys_str_mv AT zurabazmaiparashvili whenaseeminglyharmlessprescriptionturnsintotoxicity
AT kevinbryanlo whenaseeminglyharmlessprescriptionturnsintotoxicity
AT nawalhabib whenaseeminglyharmlessprescriptionturnsintotoxicity
AT anniehsieh whenaseeminglyharmlessprescriptionturnsintotoxicity