Potent RBD-specific neutralizing rabbit monoclonal antibodies recognize emerging SARS-CoV-2 variants elicited by DNA prime-protein boost vaccination

Potent RBD-specific neutralizing rabbit monoclonal antibodies recognize emerging SARS-CoV-2 variants elicited by DNA prime-protein boost vaccination

Global concerns arose as the emerged and rapidly spreading SARS-CoV-2 variants might escape host immunity induced by vaccination. In this study, a heterologous prime-boost immunization strategy for COVID-19 was designed to prime with a DNA vaccine encoding wild type (WT) spike protein receptor-bindi...

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Bibliographic Details
Main Authors: Yuxin Chen, Liguo Zhu, Weijin Huang, Xin Tong, Hai Wu, Yue Tao, Bei Tong, Haibin Huang, Jiachen Chen, Xiangan Zhao, Yang Lou, Chao Wu
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Emerging Microbes and Infections
Subjects:
SARS-CoV-2
rabbit mAb
vaccine
variant of concerns
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2021.1942227
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