Focal Hyperhidrosis Associated with Recurrent Urinary Tract Infections

Hyperhidrosis affects almost 3% of the population and is characterized by sweating that occurs in excess of that needed for normal thermoregulation. It can occur as a primary disease or secondary to underlying clinical conditions. Hyperhidrosis can stem from neurogenic sympathetic over activity invo...

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Main Authors: Dina Ismail, Vidya Madhwapathi, Evmorfia Ladoyanni
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Dermatological Medicine
Online Access:http://dx.doi.org/10.1155/2016/3842984
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author Dina Ismail
Vidya Madhwapathi
Evmorfia Ladoyanni
author_facet Dina Ismail
Vidya Madhwapathi
Evmorfia Ladoyanni
author_sort Dina Ismail
collection DOAJ
description Hyperhidrosis affects almost 3% of the population and is characterized by sweating that occurs in excess of that needed for normal thermoregulation. It can occur as a primary disease or secondary to underlying clinical conditions. Hyperhidrosis can stem from neurogenic sympathetic over activity involving normal eccrine glands. We report the interesting case of a 75-year-old male patient with a 6-month history of new onset secondary focal hyperhidrosis of buttocks, pelvis, and upper thighs. Each time his symptoms worsened he was found to have culture positive urine samples for Escherichia coli (E. coli). He underwent urological investigation and was found to have urethral strictures and cystitis. The hyperhidrosis improved each time his urinary tract infection (UTI) was treated with antibiotics and continued to remain stable with a course of prophylactic trimethoprim. We hypothesize that the patient’s urethral strictures led to inhibition in voiding which in turn increased the susceptibility to UTIs. Accumulation of urine and increased bladder pressure in turn raised sympathetic nerve discharge leading to excessive sweating. We recommend that a urine dip form part of the routine assessment of patients presenting with new onset focal hyperhidrosis of pelvis, buttocks, and upper thighs. Timely urological referral should be made for all male patients with recurrent UTI. To the authors’ knowledge, there have been no other reports of UTI-associated focal hyperhidrosis.
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spelling doaj-art-7efb6b2b05fb4a0d9ba12220da87abf62025-02-03T01:24:28ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712016-01-01201610.1155/2016/38429843842984Focal Hyperhidrosis Associated with Recurrent Urinary Tract InfectionsDina Ismail0Vidya Madhwapathi1Evmorfia Ladoyanni2Department of Dermatology, Dudley Group NHS Foundation Trust, Dudley, West Midlands DY1 2HQ, UKDepartment of Dermatology, Dudley Group NHS Foundation Trust, Dudley, West Midlands DY1 2HQ, UKDepartment of Dermatology, Dudley Group NHS Foundation Trust, Dudley, West Midlands DY1 2HQ, UKHyperhidrosis affects almost 3% of the population and is characterized by sweating that occurs in excess of that needed for normal thermoregulation. It can occur as a primary disease or secondary to underlying clinical conditions. Hyperhidrosis can stem from neurogenic sympathetic over activity involving normal eccrine glands. We report the interesting case of a 75-year-old male patient with a 6-month history of new onset secondary focal hyperhidrosis of buttocks, pelvis, and upper thighs. Each time his symptoms worsened he was found to have culture positive urine samples for Escherichia coli (E. coli). He underwent urological investigation and was found to have urethral strictures and cystitis. The hyperhidrosis improved each time his urinary tract infection (UTI) was treated with antibiotics and continued to remain stable with a course of prophylactic trimethoprim. We hypothesize that the patient’s urethral strictures led to inhibition in voiding which in turn increased the susceptibility to UTIs. Accumulation of urine and increased bladder pressure in turn raised sympathetic nerve discharge leading to excessive sweating. We recommend that a urine dip form part of the routine assessment of patients presenting with new onset focal hyperhidrosis of pelvis, buttocks, and upper thighs. Timely urological referral should be made for all male patients with recurrent UTI. To the authors’ knowledge, there have been no other reports of UTI-associated focal hyperhidrosis.http://dx.doi.org/10.1155/2016/3842984
spellingShingle Dina Ismail
Vidya Madhwapathi
Evmorfia Ladoyanni
Focal Hyperhidrosis Associated with Recurrent Urinary Tract Infections
Case Reports in Dermatological Medicine
title Focal Hyperhidrosis Associated with Recurrent Urinary Tract Infections
title_full Focal Hyperhidrosis Associated with Recurrent Urinary Tract Infections
title_fullStr Focal Hyperhidrosis Associated with Recurrent Urinary Tract Infections
title_full_unstemmed Focal Hyperhidrosis Associated with Recurrent Urinary Tract Infections
title_short Focal Hyperhidrosis Associated with Recurrent Urinary Tract Infections
title_sort focal hyperhidrosis associated with recurrent urinary tract infections
url http://dx.doi.org/10.1155/2016/3842984
work_keys_str_mv AT dinaismail focalhyperhidrosisassociatedwithrecurrenturinarytractinfections
AT vidyamadhwapathi focalhyperhidrosisassociatedwithrecurrenturinarytractinfections
AT evmorfialadoyanni focalhyperhidrosisassociatedwithrecurrenturinarytractinfections