Predictors of cytomegalovirus infection in patients with connective tissue disease treated by pulsed methylprednisolone therapy: a multicenter retrospective cohort study

Predictors of cytomegalovirus infection in patients with connective tissue disease treated by pulsed methylprednisolone therapy: a multicenter retrospective cohort study

Abstract Background Cytomegalovirus (CMV) can cause life-threatening diseases in immunosuppressed patients. Some of the patients with connective tissue disease develop CMV infection, and approximately half of this group has been reported to have received pulsed-methylprednisolone (p-MPSL) therapy. T...

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Main Authors: Haruka Ito, Takahiko Yoshimoto, Akatsuki Kokaze, Kuninobu Wakabayashi, Kazuteru Noguchi, Kiyoshi Matsui, Bunki Natsumoto, Keishi Fujio, Yutaro Hayashi, Yuko Kaneko, Takahisa Gono, Koh Okamoto, Shu Okugawa, Kyoji Moriya, Hirohiko Sueki
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Infectious Diseases
Subjects:
Cytomegalovirus
Immunosuppression
Predictors
Pulsed-methylprednisolone therapy
Immune reconstitution inflammatory syndrome
Online Access:https://doi.org/10.1186/s12879-025-10543-z
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