Gene Polymorphisms of the antioxidant enzymes NOX, GSTP, and GPX and diabetic nephropathy risk in Saudi patients with type 2 diabetes

Gene Polymorphisms of the antioxidant enzymes NOX, GSTP, and GPX and diabetic nephropathy risk in Saudi patients with type 2 diabetes

Oxidative stress has been hypothesized to play a crucial role in the complications of type 2 diabetes (T2D). Hyperglycaemia-mediated increases in free radicals have a deleterious effect on cellular compartments and nucleic acids, leading to imbalances between free radicals and antioxidant enzymes. T...

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Main Authors: Samar Sultan, Meshari Alharbi, Nuha Alrayes, Nehad Makki, Amani Alhozali, Reham Abdulnoor, Aloof Alsawat, Haitham Khalil, Noha Jawi, Ahmed Makeen
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:All Life
Subjects:
type 2 diabetes
single-nucleotide polymorphisms
genotyping
diabetic nephropathy
oxidative stress
antioxidants
Online Access:http://dx.doi.org/10.1080/26895293.2024.2391298
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