Quality of life in idiopathic pulmonary fibrosis in Latin American countries
Abstract Background Idiopathic pulmonary fibrosis (IPF) is the most common Interstitial Lung Disease (ILD). It is characterized by dyspnoea and a progressive decline in lung function, which negatively affects life. This study aimed to evaluate Health-Related Quality of Life (HRQoL) in IPF patients i...
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BMC
2025-01-01
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| Series: | BMC Pulmonary Medicine |
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| Online Access: | https://doi.org/10.1186/s12890-025-03506-2 |
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| author | H. Aguilar-Duran M. Fernández M. González-García E. Rincón-Alvarez M. Alberti F. Caro E. Tavera E. Vásquez N. Cortez M. Salinas M. Florenzano C. Florestano Ivette Buendia-Roldan |
| author_facet | H. Aguilar-Duran M. Fernández M. González-García E. Rincón-Alvarez M. Alberti F. Caro E. Tavera E. Vásquez N. Cortez M. Salinas M. Florenzano C. Florestano Ivette Buendia-Roldan |
| author_sort | H. Aguilar-Duran |
| collection | DOAJ |
| description | Abstract Background Idiopathic pulmonary fibrosis (IPF) is the most common Interstitial Lung Disease (ILD). It is characterized by dyspnoea and a progressive decline in lung function, which negatively affects life. This study aimed to evaluate Health-Related Quality of Life (HRQoL) in IPF patients in Latin American countries. Methods Six countries (Argentina, Bolivia, Colombia, Chile, Mexico, and the Dominican Republic) enrolled patients with IPF. They answered the Saint George’s Respiratory Questionnaire for Idiopathic Pulmonary Fibrosis (SGRQ-I) and the Hospital Anxiety and Depression Scale (HADS). Demographic characteristics, the Torvan index, and a lung function test were also assessed. IPF was diagnosed according to the ATS/ERS/JRS/ALAT 2018 criteria. Results We enlisted 75 patients diagnosed with IPF; 81% were male, with an average age of 74 ± 7. The total SGRQ-I score was 49 ± 23, with a higher score in the activity domain of 70 ± 23. Torvan index average was 17 ± 6. We found that 28% presented anxiety and 35% depression. Besides, we observed that patients requiring oxygen had a worse quality of life (total SGRQ-I 62 ± 22 vs. 45 ± 22, p = 0.003) without finding differences in antifibrotic therapy. We did not find differences in HRQoL when dividing groups according to their altitude above sea level, except for a higher frequency of anxiety in patients living at sea level. Conclusions We found similar data compared to those reported in real-life European populations. We also found that anxiety and depression are prevalent. However, they are often underdiagnosed and, therefore, left untreated. |
| format | Article |
| id | doaj-art-7ed26ce1876b42ab8fc9f34095cd9088 |
| institution | Kabale University |
| issn | 1471-2466 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pulmonary Medicine |
| spelling | doaj-art-7ed26ce1876b42ab8fc9f34095cd90882025-01-26T12:12:57ZengBMCBMC Pulmonary Medicine1471-24662025-01-012511810.1186/s12890-025-03506-2Quality of life in idiopathic pulmonary fibrosis in Latin American countriesH. Aguilar-Duran0M. Fernández1M. González-García2E. Rincón-Alvarez3M. Alberti4F. Caro5E. Tavera6E. Vásquez7N. Cortez8M. Salinas9M. Florenzano10C. Florestano11Ivette Buendia-Roldan12Instituto Nacional de Enfermedades Respiratorias Ismael Cosío VillegasHospital de Rehabilitación Respiratoria María FerrerFundación Neumológica ColombianaFundación Neumológica ColombianaHospital de Rehabilitación Respiratoria María FerrerHospital de Rehabilitación Respiratoria María FerrerClínica Universitaria Unión Médica del NorteCentro Médico Cardio-Neuro-Oftalmológico y TrasplanteBiomedicaInstituto Nacional del TóraxInstituto Nacional del TóraxInstituto Nacional del TóraxInstituto Nacional de Enfermedades Respiratorias Ismael Cosío VillegasAbstract Background Idiopathic pulmonary fibrosis (IPF) is the most common Interstitial Lung Disease (ILD). It is characterized by dyspnoea and a progressive decline in lung function, which negatively affects life. This study aimed to evaluate Health-Related Quality of Life (HRQoL) in IPF patients in Latin American countries. Methods Six countries (Argentina, Bolivia, Colombia, Chile, Mexico, and the Dominican Republic) enrolled patients with IPF. They answered the Saint George’s Respiratory Questionnaire for Idiopathic Pulmonary Fibrosis (SGRQ-I) and the Hospital Anxiety and Depression Scale (HADS). Demographic characteristics, the Torvan index, and a lung function test were also assessed. IPF was diagnosed according to the ATS/ERS/JRS/ALAT 2018 criteria. Results We enlisted 75 patients diagnosed with IPF; 81% were male, with an average age of 74 ± 7. The total SGRQ-I score was 49 ± 23, with a higher score in the activity domain of 70 ± 23. Torvan index average was 17 ± 6. We found that 28% presented anxiety and 35% depression. Besides, we observed that patients requiring oxygen had a worse quality of life (total SGRQ-I 62 ± 22 vs. 45 ± 22, p = 0.003) without finding differences in antifibrotic therapy. We did not find differences in HRQoL when dividing groups according to their altitude above sea level, except for a higher frequency of anxiety in patients living at sea level. Conclusions We found similar data compared to those reported in real-life European populations. We also found that anxiety and depression are prevalent. However, they are often underdiagnosed and, therefore, left untreated.https://doi.org/10.1186/s12890-025-03506-2Idiopathic pulmonary fibrosisQuality of lifeSGRQ-IHADS |
| spellingShingle | H. Aguilar-Duran M. Fernández M. González-García E. Rincón-Alvarez M. Alberti F. Caro E. Tavera E. Vásquez N. Cortez M. Salinas M. Florenzano C. Florestano Ivette Buendia-Roldan Quality of life in idiopathic pulmonary fibrosis in Latin American countries BMC Pulmonary Medicine Idiopathic pulmonary fibrosis Quality of life SGRQ-I HADS |
| title | Quality of life in idiopathic pulmonary fibrosis in Latin American countries |
| title_full | Quality of life in idiopathic pulmonary fibrosis in Latin American countries |
| title_fullStr | Quality of life in idiopathic pulmonary fibrosis in Latin American countries |
| title_full_unstemmed | Quality of life in idiopathic pulmonary fibrosis in Latin American countries |
| title_short | Quality of life in idiopathic pulmonary fibrosis in Latin American countries |
| title_sort | quality of life in idiopathic pulmonary fibrosis in latin american countries |
| topic | Idiopathic pulmonary fibrosis Quality of life SGRQ-I HADS |
| url | https://doi.org/10.1186/s12890-025-03506-2 |
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